Tomato protoplast DNA transformation: physical linkage and recombination of exogenous DNA sequences [PDF]
, 1987 Tomato protoplasts have been transformed with plasmid DNA's, containing a chimeric kanamycin resistance gene and putative tomato origins of replication.
A Crossway +38 more
core +4 more sources
Early neuronal accumulation of DNA double strand breaks in Alzheimer's disease. [PDF]
, 2019 The maintenance of genomic integrity is essential for normal cellular functions. However, it is difficult to maintain over a lifetime in postmitotic cells such as neurons, in which DNA damage increases with age and is exacerbated by multiple neurological
Adame, Anthony +8 more
core +2 more sources
Phylogenetic Resolution in Juglans Based on Complete Chloroplast Genomes and Nuclear DNA Sequences
Frontiers in Plant Science, 2017 Walnuts (Juglans of the Juglandaceae) are well-known economically important resource plants for the edible nuts, high-quality wood, and medicinal use, with a distribution from tropical to temperate zones and from Asia to Europe and Americas.
Wenpan Dong +7 more
semanticscholar +1 more source
Ratio of mitochondrial to nuclear DNA affects contamination estimates in ancient DNA analysis
Scientific Reports, 2018 In the last decade, ancient DNA research has grown rapidly and started to overcome several of its earlier limitations through Next-Generation-Sequencing (NGS).
Anja Furtwängler +9 more
semanticscholar +1 more source
The Identification of Nuclear FMRP Isoform Iso6 Partners
Cells, 2023 A deficiency of FMRP, a canonical RNA-binding protein, causes the development of Fragile X Syndrome (FXS), which is characterised by multiple phenotypes, including neurodevelopmental disorders, intellectual disability, and autism.
Nassim Ledoux +6 more
doaj +1 more source
Nuclear translocation of Cyclin B1 marks the restriction point for terminal cell cycle exit in G2 phase [PDF]
, 2014 Upon DNA damage, cell cycle progression is temporally blocked to avoid propagation of mutations. While transformed cells largely maintain the competence to recover from a cell cycle arrest, untransformed cells past the G1/S transition lose mitotic ...
Cascales, H.S. +4 more
core +4 more sources
Conformational constraints in nuclear dna [PDF]
Journal of Cell Science, 1976 ABSTRACT We have investigated DNA superstructure in a wide range of nuclei of higher cells by gently lysing cells to release structures that resemble nuclei but are depleted of nuclear proteins. The sedimentation properties of these structures, which we call nucleoids, have been examined in sucrose gradients containing the intercalating ...
Cook, P, Brazell, I
openaire +3 more sources
Circular DNA's from HeLa cell nuclei and mitochondria [PDF]
, 1970 An electron microscopic observation was made on the DNA's extracted from purified HeLa cell nuclei, mitochondria, and the whole cell, and fractionated by ethidium bromide-cesium chloride density gradient method or sucrose density gradient method. Nuclear
Hirata, Seiichi +4 more
core +1 more source
Fragmented Nuclear DNA Is the Predominant Genetic Material in Human Hair Shafts
Genes, 2018 While shed hairs are one of the most commonly encountered evidence types, they are among the most limited in terms of DNA quantity and quality. As a result, nuclear DNA short tandem repeat (STR) profiling is generally unsuccessful and DNA testing of shed
Michael D. Brandhagen +2 more
semanticscholar +1 more source
Early Steps of Hepatitis B Life Cycle: From Capsid Nuclear Import to cccDNA Formation
Viruses, 2021 Hepatitis B virus (HBV) remains a major public health concern, with more than 250 million chronically infected people who are at high risk of developing liver diseases, including cirrhosis and hepatocellular carcinoma.
João Diogo Dias +2 more
doaj +1 more source