Results 151 to 160 of about 6,649,887 (302)

An Evaluation of the Annular Fuel and Bottle-Shaped Fuel Concepts for Sodium Fast Reactors

open access: yes, 2010
Two innovative fuel concepts, the internally and externally cooled annular fuel and the bottle-shaped fuel, were investigated with the goal of increasing the power density and reduce the pressure drop in the sodium-cooled fast reactor, respectively.
Buongiorno, Jacopo   +2 more
core  

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

open access: yesFEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley   +5 more
wiley   +1 more source

Molecular engineering of Cyanine-Hoechst hybrid materials for nanoscale DNA and chromatin imaging. [PDF]

open access: yesJPhys Mater
Singh AK   +11 more
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Creys-Malville Super Phenix

open access: yes, 2009
The World's Reactors No. 73, Creys-Malville Nuclear Power Station, River Rhone (Sur le Rhone) Creys-Malville, Isere, France, Centrale Nucleaire Europeenne a Neutrons rapides SA.
Nuclear Engineering International
core  

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