Results 21 to 30 of about 7,084,452 (309)

Investigation on Shear Lugs Used in Equipment Foundations of Nuclear Engineering

Buildings
This paper investigates the shear performance of shear lugs commonly used in nuclear equipment foundations. A total of six groups of H-shaped steel shear lug specimens, six groups of angle steel shear lug specimens, and eight groups of steel plate shear ...
Yuan Gong, Xinbo Li, Chen Zhao, Yanhua Zhao   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Modular shipbuilding and its relevance to construction of nuclear power plants [PDF]

, 1988
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Nuclear Engineering, 1988.Includes bibliographical references.by Thomas W.
Seubert, Thomas W. (Thomas William)
core  

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Efficient investment allocation for improving nuclear power plant performance [PDF]

, 1999
Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept.
Li, Feng, 1968 Oct. 24-
core  

Inverse prediction of PuO2 processing conditions using Bayesian seemingly unrelated regression with functional data

Frontiers in Nuclear Engineering
Over the past decade, a variety of innovative methodologies have been developed to better characterize the relationships between processing conditions and the physical, morphological, and chemical features of special nuclear material (SNM).
Audrey Lamson McCombs, Madeline Anne Stricklin, Katherine Goode, J. Gabriel Huerta, Kurtis Shuler, J. Derek Tucker, Adah Zhang, Lucas Sweet, Daniel Ries   +8 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Economic risks of nuclear power reactor accidents [PDF]

, 1984
Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Nuclear Engineering, 1984.MICROFICHE COPY AVAILABLE IN ARCHIVES AND SCIENCE.Bibliography: leaves 326-342.by Richard P.
Burke, Richard P
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