Results 31 to 40 of about 717,626 (259)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Three-dimensional model of DEMO-FNS facility considering neutronics and radiation shield problems

open access: yesHeliyon, 2019
Recent neutronics studies of blankets for tokamak-based demonstration fusion neutron source (DEMO-FNS) showed a crucial influence of coolant composition on the transmutation rate of transuranic elements and tritium breeding in the system.
A.V. Zhirkin, B.V. Kuteev
doaj   +1 more source

Monte Carlo performance study of virtual high performance computing cluster over cloud

open access: yesRadiation Medicine and Protection, 2022
Objective: As a high computation cost discipline, nuclear science and engineering still relies heavily on traditional high performance computing (HPC) clusters.
Libing Zhu   +7 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Eugene Wigner, nuclear engineer [PDF]

open access: yesActa Physica Hungarica A) Heavy Ion Physics, 1995
Wigner led the design of the Hanford nuclear reactors and founded a school to teach reactor physics to people working in industry.
openaire   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Determination of the degree of grain refinement in irradiated U-Mo fuels

open access: yesHeliyon, 2018
A simple, repeatable method for determination of the degree of grain refinement in irradiated Uranium-Molybdenum fuels has been developed. This method involves mechanical potting and polishing of samples along with examination using a scanning electron ...
Andrew M. Casella   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

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