Results 61 to 70 of about 685,710 (239)
Development of Alternative Method for Manufacturing Structural Zirconium Elements for Nuclear Engineering. [PDF]
Materials (Basel), 2021 Ozhmegov K +4 more
europepmc +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Initiation and Development of Supercritical Carbon Dioxide Nuclear Energy and Power System
Yuanzineng kexue jishu, 2023 The supercritical carbon dioxide (S-CO2) nuclear energy and power system uses S-CO2 as the working fluid to convert nuclear heat directly or indirectly into electricity or mechanical energy.
HUANG Yanping;LIU Minyun;ZHUO Wenbin;YE Lü;TANG Jia;CHEN Yaoxing;LIU Ruilong;LIU Xiuting;TANG Yu;ZHAO Xuebin;GONG Houjun;ZAN Yuanfeng
doaj
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Yuanzineng kexue jishu, 2022 Nuclear and Radiation Safety Center, Ministry of Ecology and Environment, Beijing 102401, China;Shanghai Nuclear Engineering Research & Design Institute Co., Ltd., Shanghai 200233 ...
HEN Haiying;WANG Yichuan;HUANG Xuyang;LIU Qiaofeng;LI Wei;SUN Dawei
doaj
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Šimáně 2020: Student Conference on Nuclear Engineering
Acta Polytechnica CTU Proceedings, 2020 Nuclear-related sciences and technology have a long and rich history within the Czechoslovakia. Even though the Czech Republic and Slovakia have been separated since 1993, wide cooperation on different levels including education and research still ...
Editorial, Foreword
doaj
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Nanostructural Materials in the Nuclear Engineering
East European Journal of Physics, 2013 A brief review of research findings, pilot projects and application of nanomaterials in the nuclear power industry and engineering is presented. Examined are the prospects of creation of nanostructural materials and coatings for building blocks in NPPs ...
Nikolay Azarenkov +5 more
doaj
Isotopic Engineering—Potentials in “Nonproliferating” Nuclear Fuel
Journal of Nuclear EngineeringNuclear energy plays a critical role in global decarbonisation, but its expansion raises concerns about the proliferation risks associated with conventional fuel cycles.
Marat Margulis, Mustafa J. Bolukbasi
doaj +1 more source