Results 71 to 80 of about 7,084,452 (309)

Development of Alternative Method for Manufacturing Structural Zirconium Elements for Nuclear Engineering. [PDF]

Materials (Basel), 2021
Ozhmegov K, Kawalek A, Garbiec D, Dyja H, Arbuz A.   +4 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

PNPP-1 Philippine Nuclear Power Plant

, 2010
The World's Reactors, No. 81, PNPP-1 Philippine Nuclear Power Plant, Napot Point, Philippines.
Nuclear Engineering International
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Control of multi-module nuclear reactor stations

, 1986
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Nuclear Engineering, 1986.MICROFICHE COPY AVAILABLE IN ARCHIVES AND SCIENCEBibliography: leaves 95-97.by Matthew Jay Schor.M ...
Schor, Matthew Jay
core  

Šimáně 2020: Student Conference on Nuclear Engineering

Acta Polytechnica CTU Proceedings, 2020
Nuclear-related sciences and technology have a long and rich history within the Czechoslovakia. Even though the Czech Republic and Slovakia have been separated since 1993, wide cooperation on different levels including education and research still ...
Editorial, Foreword
doaj  

Initiation and Development of Supercritical Carbon Dioxide Nuclear Energy and Power System

Yuanzineng kexue jishu, 2023
The supercritical carbon dioxide (S-CO2) nuclear energy and power system uses S-CO2 as the working fluid to convert nuclear heat directly or indirectly into electricity or mechanical energy.
HUANG Yanping;LIU Minyun;ZHUO Wenbin;YE Lü;TANG Jia;CHEN Yaoxing;LIU Ruilong;LIU Xiuting;TANG Yu;ZHAO Xuebin;GONG Houjun;ZAN Yuanfeng
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Isotopic Engineering—Potentials in “Nonproliferating” Nuclear Fuel

Journal of Nuclear Engineering
Nuclear energy plays a critical role in global decarbonisation, but its expansion raises concerns about the proliferation risks associated with conventional fuel cycles.
Marat Margulis, Mustafa J. Bolukbasi
doaj   +1 more source