Results 91 to 100 of about 6,649,887 (302)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Šimáně 2023 – International Student Conference on Nuclear Engineering
Acta Polytechnica CTU Proceedings, 2023 Nuclear-related sciences and technology have a long and rich history within the Czechoslovakia. Even though the Czech Republic and Slovakia have been separated since 1993, wide cooperation on different levels including education and research still ...
Editorial Foreword
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Isotopic Engineering—Potentials in “Nonproliferating” Nuclear Fuel
Journal of Nuclear EngineeringNuclear energy plays a critical role in global decarbonisation, but its expansion raises concerns about the proliferation risks associated with conventional fuel cycles.
Marat Margulis, Mustafa J. Bolukbasi
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Nanostructural Materials in the Nuclear Engineering
East European Journal of Physics, 2013 A brief review of research findings, pilot projects and application of nanomaterials in the nuclear power industry and engineering is presented. Examined are the prospects of creation of nanostructural materials and coatings for building blocks in NPPs ...
Nikolay Azarenkov +5 more
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Engineering of Nuclear Reactors
, 2007 This course covers the engineering principles of nuclear reactors, emphasizing power reactors. Specific topics include power plant thermodynamics, reactor heat generation and removal (single-phase as well as two-phase coolant flow and heat transfer), and
Buongiorno, Jacopo
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
The Offshore Floating Nuclear Plant Concept
, 2016 A new offshore floating nuclear plant (OFNP) concept with high potential for attractive economics and an unprecedented level of safety is presented. OFNP creatively combines state-of-the-art light water reactors and floating platforms similar to those ...
Buongiorno, Jacopo +3 more
core +1 more source
Yuanzineng kexue jishu, 2022 Nuclear and Radiation Safety Center, Ministry of Ecology and Environment, Beijing 102401, China;Shanghai Nuclear Engineering Research & Design Institute Co., Ltd., Shanghai 200233 ...
HEN Haiying;WANG Yichuan;HUANG Xuyang;LIU Qiaofeng;LI Wei;SUN Dawei
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