Results 101 to 110 of about 8,941,785 (363)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Open heavy flavor production at LHCb [PDF]

EPJ Web of Conferences
The LHCb experiment is a dedicated heavy-flavor experiment at the LHC and is uniquely well-suited to studying heavy-flavor production in heavyion collisions.
Wang Jianqiao
doaj   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Heavy-flavour production in Pb-Pb collisions at the LHC, measured with the ALICE detector

, 2011
We present the first results from the ALICE experiment on the nuclear modification factors for heavy-flavour hadron production in Pb-Pb collisions at sqrt{s_NN}=2.76 TeV. Using proton-proton and lead-lead collision samples at sqrt{s}=7 TeV and sqrt{s_NN}=
Aamodt K, Andrea Dainese, Averbeck R Bastid N Conesa del Valle Z Dainese A Zhang X, Cacciari M, Cacciari M Greco M Nason P, Kniehl B A, Martinez-Garcia G, Masciocchi S, Pachmayer Y, Pillot P, Rossi A, Zhang X   +11 more
core   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Double-beta decay of $$^{150}\hbox {Nd}$$ 150 Nd to excited levels of $$^{150}\hbox {Sm}$$ 150 Sm

European Physical Journal C: Particles and Fields
The $$2\nu 2\beta $$ 2 ν 2 β decay of $$^{150}\hbox {Nd}$$ 150 Nd to the first excited 740.5 keV $$0^{+}_{1}$$ 0 1 + level of $$^{150}\hbox {Sm}$$ 150 Sm was measured over 5.845 years with the help of a four-crystal low-background HPGe $$\gamma $$ γ ...
A. S. Barabash, P. Belli, R. Bernabei, R. S. Boiko, F. Cappella, V. Caracciolo, R. Cerulli, F. A. Danevich, D. L. Fang, F. Ferella, A. Incicchitti, V. V. Kobychev, S. I. Konovalov, M. Laubenstein, A. Leoncini, V. Merlo, S. Nisi, O. Niţescu, D. V. Poda, O. G. Polischuk, I. B.-K. Shcherbakov, F. Šimkovic, A. Timonina, V. S. Tinkova, V. I. Tretyak, V. I. Umatov   +25 more
doaj   +1 more source

Search of non-standard strong gravity at nuclear scale using electron spin geodetic precession

EPJ Web of Conferences, 2014
The MTV-G project was started in 2011 to explore a strong gravitational field at a nuclear scale in an electron double scattering experiment, utilizing an experimental technique of the MTV experiment, which searches a electron’s T-Violating transverse ...
Tanaka Saki, Nakaya Yusuke, Narikawa Reiya, Ninomiya Kazufumi, Onishi Junichi, Pearson Matthew, Openshaw Robert, Saiba Shuntaro, Tanuma Ryosuke, Totsuka Yumi, Murata Jiro   +10 more
doaj   +1 more source

Study of Luminescence in Noble Gases and Binary Kr-Xe Mixture Excited by the Products of 6Li(n,α)T Nuclear Reaction

Eurasian Chemico-Technological Journal, 2019
At the present time the direct nuclear energy conversion into optical radiation is realized in gas media in which filling of energy levels takes place in the low-temperature plasma (nuclear-excited plasma) induced by ionizing radiation.
K. Samarkhanov, E. Batyrbekov, M. Khasenov, Yu. Gordienko, Zh. Zaurbekova, V. Bochkov   +5 more
doaj   +1 more source

Cysteamine in Maturation Medium Enhances Nuclear Maturation and Fertilization Rate of Sheep Oocytes In Vitro

Hayati Journal of Biosciences, 2020
Low nuclear maturation and fertilization rate is one obstacle in the in vitro embryo production which decrease embryo yield. This problem is presumable related with high production of reactive oxygen species (ROS) during maturation process.
Feni Dwi Kartika Gulo, Ni Wayan Kurniani Karja, Mohamad Agus Setiadi   +2 more
doaj   +1 more source

Nuclear Niño Experiments

, 2020
CESM source code modifications to inject soot into the model. Albedo modification files to simulate nuclear winter conditions by changing the albedo of the land surface in the radiation model.
openaire   +1 more source