Results 131 to 140 of about 8,941,785 (363)
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Editorial: Benchmark experiments, development and needs in support of advanced reactor design
Frontiers in Energy Research, 2023 Mark D. DeHart +3 more
doaj +1 more source
, 2003 The recent results from resonance production in central Au+Au and p+p collisions at $\sqrt{s_{\rm NN}} = $ 200 GeV from the STAR experiment at RHIC are presented and discussed.Comment: 7 pages, proceedings 19th Winter Workshop on Nuclear Dynamics ...
Blyth, Charles +5 more
core +1 more source
Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source
, 2008 The OPERA experiment, whose aim is the direct observation of nu_mu ~> nu_tau oscillations in appearance mode in the CNGS high-energy neutrino beam, consists of a high-granularity modular target of nuclear emulsions-lead "bricks", richly instrumented with
Longhin, Andrea
core
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
Enhancing Electrotransfection Efficiency through Improvement in Nuclear Entry of Plasmid DNA
Molecular Therapy: Nucleic Acids, 2018 The nuclear envelope is a physiological barrier to electrogene transfer. To understand different mechanisms of the nuclear entry for electrotransfected plasmid DNA (pDNA), the current study investigated how manipulation of the mechanisms could affect ...
Lisa D. Cervia +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Progress in constraining the asymmetry dependence of the nuclear caloric curve
EPJ Web of Conferences, 2016 The nuclear equation of state is a basic emergent property of nuclear material. Despite its importance in nuclear physics and astrophysics, aspects of it are still poorly constrained.
McIntosh Alan B., Yennello Sherry J.
doaj +1 more source