Results 131 to 140 of about 592,569 (248)

Real-Time event reconstruction for Nuclear Physics Experiments using Artificial Intelligence [PDF]

Gagik Gavàlian
openalex   +1 more source

Upgrading the Baryonic Matter at the Nuclotron Experiment at NICA for Studies of Dense Nuclear Matter [PDF]

, 2019
Peter Senger, D. Dementev, Johann M. Heuser, M. Kapishin, E. Lavrik, Yuri Murin, Anna Maksymchuk, Hans Rudolf Schmidt, C. Schmidt, A. Senger, A. Zinchenko   +10 more
openalex   +1 more source

Binding energy shifts from heavy-ion experiments in a nuclear statistical equilibrium model

, 2021
S. Mallik, Helena Pais, F. Gulminelli
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Direct observation of the Migdal effect induced by neutron bombardment. [PDF]

Nature
Yi D, Liu Q, Chen S, Dong C, Feng H, Gao C, Huang W, Jing X, Kong L, Li J, Li P, Liang E, Ma R, Su C, Su L, Sun J, Wang D, Wang J, Wei Z, Yao Z, Yu Y, Zhang Y, Zhou S, Zhou Z, Zhu B, Zuo J, Liu H, Sun X, Wu L, Zheng Y.   +29 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Constraining the impact of chlorine as a neutron absorber in next-gen fast reactor designs. [PDF]

Sci Rep
Hanselman K, Allan IJ, Kuvin SA, Kawano T, Kleedtke N, Lee HY, Paneru SN, Thompson N, Winkelbauer J, Cisneros T, Harper B, Wargon M.   +11 more
europepmc   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Endoplasmic reticulum disruption stimulates nuclear membrane mechanotransduction. [PDF]

Nat Cell Biol
Shen Z, Gelashvili Z, Niethammer P.
europepmc   +1 more source

Summary of the available evidence for the physical association of nuclear TFs with the mitochondrial genome. All TFs with ChIP-seq evidence for chrM occupancy are listed in the “any” column. “BPNet confirmed” indicates that the observed ChIP-Seq pattern is corroborated in its key aspects by BPNet models. The “discordant” TFs are those for which not all available ChIP-seq experiments show chrM peaks.

Georgi K Marinov (2863319), Vivekanandan Ramalingam (20969107), William J Greenleaf (14133552), Anshul Kundaje (269741)   +3 more
openalex   +1 more source