Results 1 to 10 of about 526,949 (124)

Protective effects of nattokinase against microvasculopathy and neuroinflammation in diabetic retinopathy 纳豆激酶对糖尿病视网膜病变微血管病变和神经炎症的保护作用

open access: yesJournal of Diabetes, Volume 15, Issue 10, Page 866-880, October 2023., 2023
Highlights Nattokinase rescued endothelial dysfunction and pericyte loss in the diabetic retina. Nattokinase attenuated diabetes‐induced retinal inflammation and neurodegeneration. High mobility group box 1 signaling was involved in nattokinase‐mediated retinal protection.
Zijing Huang   +11 more
wiley   +1 more source

CatMass: software for calculating optimal sample masses for X‐ray absorption spectroscopy experiments involving complex sample compositions

open access: yesJournal of Synchrotron Radiation, Volume 30, Issue 5, Page 1023-1029, September 2023., 2023
CatMass is a new software for calculating the optimal sample mass of samples with complex compositions (e.g. a supported metal catalyst mixed with a diluent) for X‐ray absorption and X‐ray scattering experiments with supplemental results to guide experimental design and collection geometry.This paper presents software for calculating the optimal mass ...
Jorge E. Perez-Aguilar   +3 more
wiley   +1 more source

Tumour cells are sensitised to ferroptosis via RB1CC1‐mediated transcriptional reprogramming

open access: yesClinical and Translational Medicine, Volume 12, Issue 2, February 2022., 2022
Nuclear translocation of RB1CC1 sensitises tumour cells to ferroptosis. Phosphorylation at S537 by JNK is prerequisite for RB1CC1 to translocate into nucleus. RB1CC1 recruits ELP3 to reinforce H4K12Ac within ferroptosis‐associated enhancers, and RB1CC1 activates transcriptional reprogramming to enhance mitochondrial function. RB1CC1 is an indispensible
Xiangfei Xue   +12 more
wiley   +1 more source

Gastrodin induces lysosomal biogenesis and autophagy to prevent the formation of foam cells via AMPK‐FoxO1‐TFEB signalling axis

open access: yesJournal of Cellular and Molecular Medicine, Volume 25, Issue 12, Page 5769-5781, June 2021., 2021
Abstract Abnormal accumulation of lipids and massive deposition of foam cells is a primary event in the pathogenesis of atherosclerosis. Recent studies have demonstrated that autophagy and lysosomal function of atherosclerotic macrophages are impaired, which exacerbates the accumulation of lipid in macrophages and formation of foam cells.
Jun Tao   +7 more
wiley   +1 more source

Glutamine Metabolism in Osteoprogenitors Is Required for Bone Mass Accrual and PTH‐Induced Bone Anabolism in Male Mice

open access: yesJournal of Bone and Mineral Research, Volume 36, Issue 3, Page 604-616, March 2021., 2021
ABSTRACT Skeletal homeostasis critically depends on the proper anabolic functioning of osteolineage cells. Proliferation and matrix synthesis are highly demanding in terms of biosynthesis and bioenergetics, but the nutritional requirements that support these processes in bone‐forming cells are not fully understood.
Steve Stegen   +5 more
wiley   +1 more source

A promising PET tracer candidate targeting α‐synuclein inclusions

open access: yes, 2023
Clinical and Translational Medicine, Volume 13, Issue 9, September 2023.
Jie Xiang, Zhentao Zhang, Keqiang Ye
wiley   +1 more source

Retracted: MicroRNA let‐7b Inhibits Proliferation and Induces Apoptosis of Castration‐Resistant Prostate Cancer Cells by Blocking the Ras/Rho Signaling Pathway via NRAS

open access: yesClinical and Translational Science, Volume 14, Issue 5, Page 2055-2064, September 2021., 2021
Retraction: Huang, L., Wang, L., Wang, L., Wu, Z., Jiang, F., Li, Q., & Wang, S. MicroRNA let‐7b Inhibits Proliferation and Induces Apoptosis of Castration‐Resistant Prostate Cancer Cells by Blocking the Ras/Rho Signaling Pathway via NRAS, Clin. Trans. Sci.
wiley   +1 more source

Nuclear rho transparencies in a relativistic Glauber model [PDF]

open access: yes, 2013
[Background] The recent Jefferson Lab data for the nuclear transparency in $\rho^ {0}$ electroproduction have the potential to settle the scale for the onset of color transparency (CT) in vector meson production.
Cosyn, Wim, Ryckebusch, Jan
core   +2 more sources

Coulomb and nuclear breakup of a halo nucleus 11Be [PDF]

open access: yes, 2004
Breakup reactions of the one-neutron halo nucleus 11Be on Pb and C targets at about 70 MeV/u have been investigated by measuring the momentum vectors of the incident 11Be, outgoing 10Be, and neutron in coincidence.
Aoi, N.   +15 more
core   +3 more sources

On a Missed Mechanism of Dielectron Production in Nucleon-Nucleon Collisions

open access: yes, 2010
We examine a new mechanism of $e^+e^-$ pair production in $NN$ collisions associated with the $NN$-decoupled dibaryon $d^\star_1$(1956) formation in the process $NN \to \gamma^\star d^\star_1$, where $\gamma^\star$ is the virtual photon which converts ...
Khrykin, Anatoliy S.
core   +1 more source

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