Results 51 to 60 of about 2,405,307 (307)
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Reformulated Multiple Shear Mechanism Model for Fast 3D Nonlinear Ground Motion Analysis
GeosciencesWe have proposed the reduction in triple integral to double integral that is used in multiple shear mechanism model for faster 3D nonlinear ground motion analysis.
Yoshihiro Shishikura +2 more
doaj +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Virtual and Physical PrototypingAluminum matrix boron carbide (B4C/Al) composites with moderate strength but excellent ductility are fabricated by laser-directed energy deposition (LDED) with different laser powers.
Weiwei Xiao +7 more
doaj +1 more source
Microstructural, mechanical properties and high temperature oxidation of Cr, Al-coated Zr-4 alloy
Nuclear Materials and Energy, 2020 Cr and Al coating were respectively deposited on Zr-4 alloy by magnetron sputtering and high temperature oxidation (HTO) tests were conducted in air environment at 1200 °C for 3 h for Cr-coated and Al-coated specimens.
Jinghao Huang +8 more
doaj +1 more source
The UNISOR nuclear orientation facility [PDF]
Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 1989 Abstract The combination of an on-line isotope separator and a dilution refrigerator has increased the applicability of the nuclear orientation technique to a wide range of nuclei, especially those very far from stability. The UNISOR nuclear orientation facility (UNISOR/NOF) has recently become operational.
openaire +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Generation of Coupled Nonlinear Oscillations in Charged-Particle Beam by Crossed Magnetic Fields
Quantum Beam ScienceBased on the cold-fluid hydrodynamic description, the interaction of a non-relativistic charged-particle beam with crossed magnetic fields is studied.
Alexander R. Karimov +3 more
doaj +1 more source