Results 241 to 250 of about 2,214,209 (304)

Senkyunolide I Inhibits mtDNA‐cGAS‐STING Signaling in Macrophages via Targeting VDAC1 Oligomerization to Attenuate Ulcerative Colitis

open access: yesAdvanced Science, EarlyView.
In macrophages, senkyunolide I (SEI) directly targets the K12 residue of VDAC1 to inhibit its stress‐induced oligomerization, a critical upstream event that effectively prevents mitochondrial DNA release and subsequent cGAS‐STING pathway activation.
Zhiming Ye   +9 more
wiley   +1 more source

Nanoscale Confinement Enhances Ultrafast Demagnetization

open access: yesAdvanced Science, EarlyView.
Next generation spintronics may depend on successfully combining femtosecond spin dynamics with nanoscale device miniaturization. We address this by systematically studying the effect of nanoscale confinement on the femtosecond demagnetization of Iron. By combining ultrafast experiments sensitive to spins, charge carriers, and phonons, we uncover a nm ...
Yoav William Windsor   +23 more
wiley   +1 more source

Interfacial Electric Field Engineering of High‐Entropy Heterostructures Triggering Self‐Limiting Reconstruction for Industrial‐Scale Electrocatalysis

open access: yesAdvanced Science, EarlyView.
An interfacial electric field engineering strategy is proposed to trigger the self‐limiting surface reconstruction of high‐entropy heterostructures. Driven by this built‐in field, the controlled sacrificial leaching of W evolves a robust active layer, enabling exceptional oxygen evolution performance and ultrastability at ampere‐level current densities
Liang Yan   +4 more
wiley   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li   +9 more
wiley   +1 more source

Stabilising the Lattice Oxygen Oxidation Mechanism Through Iridium Single Atoms in Chromium‐Doped Cobalt Iron Layered Double Hydroxides

open access: yesAdvanced Science, EarlyView.
Iridium single atoms and Cr doping synergistically activate and stabilise the lattice oxygen oxidation mechanism in CoFe layered double hydroxides. Electronic modulation enhances metal–oxygen covalency, suppresses over‐oxidation, and enables durable oxygen evolution, delivering high‐performance anion exchange membrane water electrolysis with ...
Parisa Eskandari   +13 more
wiley   +1 more source

Electrocatalytic CO2 Reduction over Sn‐Cu Bimetallic Catalysts Synthesized via an Amalgamated Lithium Metal Method

open access: yesAdvanced Science, EarlyView.
An amalgamated lithium metal method enables systematic control of Sn–Cu active‐site dimensions from isolated atoms to nanocrystallites. Increasing the metal loading shifts CO2 electroreduction selectivity from acetaldehyde on highly dispersed Sn–Cu sites to formate on Sn‐rich crystallites, revealing how bimetallic dispersion and local coordination ...
Minghao Xie   +6 more
wiley   +1 more source

Fueling Nuclear Starbursts

Symposium - International Astronomical Union, 1999
We present a numerical simulation of two merging equal-mass, gas-rich disk galaxies. Special emphasis is given to an accurate treatment of the interstellar medium physics and star formation with its feedback. We will explain how the negative feedback from young stars restricts the bulk of the star formation during the merger-induced starburst to the ...
Gerritsen, J P E, Icke, V
openaire   +2 more sources

Nuclear Fuel Hazards

JAMA: The Journal of the American Medical Association, 1973
To the Editor.— Many of the points emphasized by Press "Nuclear and Fossil-Fueled Plants Generating Electricity" (22:1281, 1972) need to be thoroughly developed so that physicians are properly informed of the environmental hazards of nuclear generating plants. Dr. Press listed only one reference—M.
openaire   +2 more sources

Nuclear-Fueled Cardiac Pacemakers

Chest, 1974
Nuclear-fueled cardiac pacemakers have reached the stage of clinical evaluation. Approximately 600 units have been implanted in patients. Such pacemakers have the potential of long life. Studies on animals indicate that the somatic and genetic effects from such sealed sources do not preclude clinical use.
F N, Huffman, J C, Norman
openaire   +2 more sources

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