Results 41 to 50 of about 595,659 (257)

Liquid chromatographic determination of enantiomeric purity of [11C]methyl-L-methionine and O-(2-[18F]fluoroethyl)-L-tyrosine by pre-column derivatization with o-phthaldialdehyde and N-isobutyryl-L-cysteine

EJNMMI Radiopharmacy and Chemistry
Background [11C]methyl-L-methionine ([11C]MET) and O-(2-[18F]fluoroethyl)-L-tyrosine ([18F]FET) are commonly used radiopharmaceuticals in positron emission tomography (PET) for diagnosis of brain tumors.
Viktória Forgács, Viktória Balla, Viktória Csonka, Dezső Szikra, Dániel Szücs, Enikő Németh, Zita Képes, György Trencsényi, István Jószai   +8 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Continuous bed motion versus step-and-shoot acquisition in LAFOV PET/CT: insights from multi-phantom and patient studies

EJNMMI Physics
Background Continuous bed motion (CBM) allows flexible extension of the scan range compared to conventional step‑and‑shoot (S&S) acquisition but has not yet been evaluated in long axial field‑of‑view (LAFOV) PET/CT. This study systematically assessed the
P. M. Linder, W. Lan, E. Calderón, I. Rausch, C. la Fougère, F. P. Schmidt   +5 more
doaj   +1 more source

Imaging angiogenesis in atherosclerosis in large arteries with 68Ga-NODAGA-RGD PET/CT: relationship with clinical atherosclerotic cardiovascular disease

EJNMMI Research, 2021
Background Integrin alpha-V-beta-3 (αvβ3) pathway is involved in intraplaque angiogenesis and inflammation and represents a promising target for molecular imaging in cardiovascular diseases such as atherosclerosis. The aim of this study was to assess the
Matthieu Dietz, Christel H. Kamani, Emmanuel Deshayes, Vincent Dunet, Periklis Mitsakis, George Coukos, Marie Nicod Lalonde, Niklaus Schaefer, John O. Prior   +8 more
doaj   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Regional impact of time-to-equilibrium on indirect Patlak whole-body parametric imaging: a multi-tissue class analysis at the entire body level

EJNMMI Physics
Purpose Patlak parametric imaging is widely employed for kinetic modeling due to its simplicity and robustness. The time-to-equilibrium (t*), which must be defined to estimate kinetic parameters, is currently set empirically and uniformly across the ...
Abarnaa Sivapathasundaram, Agnieszka Buffon, Jérôme Ghidaglia, Yannick Jentreau, Léa Gomez, Axelle Jamet, Maïwenn Beau, Natacha Da Fonseca, Kevin Harnais, Stéphane Onephandara, Widad Makhlouf, Karim En Nourhi, Emmanuel Durand, Sylvain Faure, Florent L. Besson   +14 more
doaj   +1 more source

Performance characteristic evaluation of a bismuth germanate-based high-sensitivity 5-ring discovery image quality positron emission tomography/computed tomography system as per National Electrical Manufacturers Association NU 2-2012

World Journal of Nuclear Medicine, 2019
National Electrical Manufacturers Association (NEMA) provides guidelines to assess the performance of Positron Emission Tomography (PET). A PET/CT scanner, Discovery IQ, GE Medical systems, Milwaukee, USA was installed in our department which has high a ...
Ashish Jha, Sneha Mithun, Ameya Puranik, Nilendu Purandare, Sneha Shah, Archi Agrawal, Venkatesh Rangarajan   +6 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Breast cancer metastasis to the colon mimicking primary colorectal carcinoma

EJNMMI Reports
Breast cancer metastasis to the colon is rare, occurring in less than 1% of patients with metastatic breast cancer. Invasive lobular carcinoma (ILC) exhibits a distinct tropism for the gastrointestinal tract and adnexa, often presenting with atypical ...
Qingkui Liu, Jianheng Gao, Hongxing Yang, Xiaoshan Chen, Yaqi He   +4 more
doaj   +1 more source

Nuclear Imaging of Neuroendocrine Tumors

Surgical Oncology Clinics of North America, 2020
Consensus guidelines acknowledge the role of gallium Ga-68 (68Ga) 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetic (DOTA) somatostatin receptor (SSTR) positron emission tomography/computed tomography (PET/CT) in management of neuroendocrine tumor (NET) patients.
Janet, Pollard, Parren, McNeely, Yusuf, Menda   +2 more
openaire   +3 more sources