Results 11 to 20 of about 3,438,672 (302)

Nuclear magnetic resonance [PDF]

open access: yes, 2012
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32166This article reviews the principles and methods of nuclear magnetic resonance spectroscopy, and gives examples of applications carried out at our Facility, which illustrate the ...
Molins i Montserrat, Mª Antònia   +4 more
core   +7 more sources

Conformational dynamics in GPCR signaling by NMR

open access: yesMagnetic Resonance Letters, 2022
G-protein-coupled receptors (GPCRs) mediate a wide range of cellular responses to various ligands or stimuli, and are the most important drug targets associated with human diseases.
Yunfei Hu, Changwen Jin
doaj   +1 more source

Comparison of Image Quality and Radiation Dose Between Single-Energy and Dual-Energy Images for the Brain With Stereotactic Frames on Dual-Energy Cerebral CT

open access: yesFrontiers in Radiology, 2022
BackgroundPreoperative stereotactic planning of deep brain stimulation (DBS) using computed tomography (CT) imaging in patients with Parkinson's disease (PD) is of clinical interest. However, frame-induced metal artifacts are common in clinical practice,
Xiaojing Zhao   +13 more
doaj   +1 more source

Cervicocephalic Spotty Calcium for the Prediction of Coronary Atherosclerosis in Patients With Acute Ischemic Stroke

open access: yesFrontiers in Neurology, 2021
Purpose: To investigate the characteristics of cervicocephalic spotty calcium (SC) and coronary atherosclerosis in patients with acute ischemic stroke (AIS) and to assess the predictive value of SC for coronary atherosclerosis using combined coronary and
Chong Zheng   +13 more
doaj   +1 more source

The DNA Recognition Motif of GapR Has an Intrinsic DNA Binding Preference towards AT-rich DNA

open access: yesMolecules, 2021
The nucleoid-associated protein GapR found in Caulobacter crescentus is crucial for DNA replication, transcription, and cell division. Associated with overtwisted DNA in front of replication forks and the 3′ end of highly-expressed genes, GapR can ...
Qian Huang   +4 more
doaj   +1 more source

Distinct activation mechanisms of β-arrestin-1 revealed by 19F NMR spectroscopy

open access: yesNature Communications, 2023
β-Arrestins (βarrs) are functionally versatile proteins that play critical roles in the G-protein-coupled receptor (GPCR) signaling pathways. While it is well established that the phosphorylated receptor tail plays a central role in βarr activation ...
Ruibo Zhai   +6 more
doaj   +1 more source

Contrasting Properties of Polymeric Nanocarriers for MRI-Guided Drug Delivery

open access: yesNanomaterials, 2023
Poor pharmacokinetics and low aqueous solubility combined with rapid clearance from the circulation of drugs result in their limited effectiveness and generally high therapeutic doses.
Natalia Łopuszyńska   +1 more
doaj   +1 more source

Predictive value of baseline metabolic tumor burden on 18F-FDG PET/CT for brain metastases in patients with locally advanced non-small-cell lung cancer

open access: yesFrontiers in Oncology, 2022
ObjectivesBrain metastases (BMs) are a major cause leading to the failure of treatment management for non-small-cell lung cancer (NSCLC) patients. The purpose of this study was to evaluate the predictive value of baseline metabolic tumor burden on 18F ...
Jingjie Shang   +9 more
doaj   +1 more source

Design, Characterization and Molecular Modeling of New Fluorinated Paramagnetic Contrast Agents for Dual 1H/19F MRI

open access: yesMagnetochemistry, 2020
One major goal in medical imaging is the elaboration of more efficient contrast agents (CAs). Those agents need to be optimized for the detection of affected tissues such as cancers or tumors while decreasing the injected quantity of agents.
Emilie Hequet   +8 more
doaj   +1 more source

Zero- to Ultralow-Field Nuclear Magnetic Resonance Enhanced with Dissolution Dynamic Nuclear Polarization [PDF]

open access: yes, 2022
Zero- to ultralow-field nuclear magnetic resonance is a modality of magnetic resonance experiment which does not require strong superconducting magnets. Contrary to conventional high-field nuclear magnetic resonance, it has the advantage of allowing high
Morgan, Ceillier   +9 more
core   +1 more source

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