Results 91 to 100 of about 1,052,179 (350)
A new window on Strange Quark Matter as the ground state of strongly interacting matter
, 2003 If strange quark matter is the true ground state of matter, it must have lower energy than nuclear matter. Simultaneously, two-flavour quark matter must have higher energy than nuclear matter, for otherwise the latter would convert to the former. We show,
A. Gocksch +21 more
core +2 more sources
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Compact stars with sequential QCD phase transitions
, 2017 Compact stars may contain quark matter in their interiors at densities exceeding several times the nuclear saturation density. We explore models of such compact stars where there are two first-order phase transitions: the first from nuclear matter to a ...
Alford, Mark G., Sedrakian, Armen
core +2 more sources
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Physical Review C, 2016 It is generally considered that an atomic nucleus is always compact. Based on the isospin-dependent Boltzmann nuclear transport model, here I show that large block nuclear matter or excited nuclear matter may both be hollow. And the size of inner bubble in these matter is affected by the charge number of nuclear matter.
openaire +2 more sources
Dense Stellar Matter with Strange Quark Matter Driven by Kaon Condensation
, 2011 The core of neutron-star matter is supposed to be at a much higher density than the normal nuclear matter density for which various possibilities have been suggested such as, for example, meson or hyperon condensation and/or deconfined quark or color ...
Kim, Kyungmin +2 more
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Nuclear shock waves in heavy-ion collisions [PDF]
, 2006 It is shown that nuclear matter is compressed during the encounter of heavy ions. If the relative velocity of the nuclei is larger than the velocity of first sound in nuclear matter (compression sound for isospin T=0), nuclear shock waves occur.
Greiner, Walter +2 more
core
Towards a holographic quark-hadron continuity
, 2019 We study dense nuclear and quark matter within a single microscopic approach, namely the holographic Sakai-Sugimoto model. Nuclear matter is described via instantons in the bulk, and we show that instanton interactions are crucial for a continuous ...
Fadafan, Kazem Bitaghsir +2 more
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source