Results 121 to 130 of about 199,440 (313)

PION CONDENSATION IN A FIELD THEORY CONSISTENT WITH BULK PROPERTIES OF NUCLEAR MATTER [PDF]

, 1980
Pion condensation is investigated in a self-consistent. relativistic mean field theory that is constrained to reproduce the bulk properties of nuclear matter.
Gyulassy, M., Banerjee, B., Glendenning, N.K.   +2 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Dynamic nuclear polarization of 67Zn and 1H spins by means of shallow donors in ZnO nanoparticles

, 2009
Dynamic nuclear polarization DNP effects are observed of 67Zn I=5/2 nuclear spins in ZnO nanoparticles and of 1H I=1/2 spins of the Zn OH 2 capping layer.
Mello Donega, C. de, Orlinskii, S.B., Condensed Matter and Interfaces, Meijerink, A., Baranov, P.G., Sub Condensed Matter and Interfaces, Schmidt, J., de Mello Donegá, C.   +7 more
core   +1 more source

An analysis of the features of charged hadron production in collisions of bismuth nuclei at an energy of 9.2 GeV using the Blast-Wave model

St. Petersburg Polytechnical University Journal: Physics and Mathematics
The paper presents charged hadron invariant spectra obtained in Bi+Bi collisions at an energy of 9.2 GeV on the basis of simulation performed using the UrQMD hybrid generator and the MPDroot package.
Larionova Daria, Berdnikov Yaroslav, Kotov Dmitry   +2 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Dynamical nuclear polarization and confinement effects in ZnO quantum dots

, 2010
The spatial distribution of the electronic wave function of a shallow donor (SD) in a ZnO semiconductor quantum dots (QD's) has been determined in the regime of quantum confinement by using the nuclear spins as probes.
Orlinskii, S.B., Jan Schmidt, Condensed Matter and Interfaces, Celso de Mello Donegá, Baranov, P.G., Hofmann, D.M., Pavel G. Baranov, de Mello Donega, C., Sergei B. Orlinskii, Meijerink, A., Andries Meijerink, Detlev M. Hofmann, Sub Condensed Matter and Interfaces, Schmidt, J.   +13 more
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Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Lecture notes on phase transformations in nuclear matter

, 2000
The atomic nucleus, despite of being one of the smallest objects found in nature, appears to be large enough to experience phase transitions. The book deals with the liquid and gaseous phases of nuclear matter, as well as with the experimental routes ...
Dorso, Claudio O, López, Jorge A
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