Results 171 to 180 of about 4,553,635 (397)

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

Multifragmentation, Clustering, and Coalescence in Nuclear Collisions [PDF]

open access: yes, 2005
Nuclear collisions at intermediate, relativistic, and ultra-relativistic energies offer unique opportunities to study in detail manifold fragmentation and clustering phenomena in dense nuclear matter. At intermediate energies, the well known processes of
Scherer, Stefan, Stocker, Horst
core   +2 more sources

Light Front Theory Of Nuclear Matter

open access: yes, 1999
A relativistic light front formulation of nuclear dynamics is applied to infinite nuclear matter. A hadronic meson-baryon Lagrangian, consistent with chiral symmetry, leads to a nuclear eigenvalue problem which is solved, including nucleon-nucleon (NN ...
Alde   +13 more
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Revalidation of the isobaric multiplet mass equation at A=53, T=3/2

open access: yesPhysics Letters B, 2016
The T=3/2 isobaric analog state (IAS) in 53Co is firmly established through a comprehensive measurement of β-delayed γ and proton decay of 53Ni. The determined excitation energy of 53Co IAS combined with the mass of 53Co generates a precise mass excess ...
J. Su   +39 more
doaj   +1 more source

Empirical information on nuclear matter fourth-order symmetry energy from an extended nuclear mass formula

open access: yes, 2017
We establish a relation between the equation of state (EOS) of nuclear matter and the fourth-order symmetry energy $a_{\rm{sym,4}}(A)$ of finite nuclei in a semi-empirical nuclear mass formula by self-consistently considering the bulk, surface and ...
Chen, Lie-Wen, Wang, Rui
core   +2 more sources

Hadronization in Cold Nuclear Matter [PDF]

open access: yesNuclear Physics A, 2007
I review a recently proposed scaling analysis of hadron suppression in Deeply Inelastic Scattering on nuclear targets measured at the HERMES experiment. The analysis can distinguish 2 competing explanations for the observed suppression, namely, quark radiative energy loss with long hadron formation times, and prehadron nuclear absorption with ...
openaire   +2 more sources

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

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