Results 81 to 90 of about 1,042,247 (302)

The Flow Constraint Influence on the Properties of Nuclear Matter Critical Endpoint [PDF]

open access: yes, 2017
We propose a novel family of equations of state for symmetric nuclear matter based on the induced surface tension concept for the hard-core repulsion.
Bravina, L. V.   +4 more
core   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Hypercollapsed Nuclear Matter [PDF]

open access: yesSymposium - International Astronomical Union, 1974
We evoke the possible existence of hypercollapsed tightly bound nuclear isomers, due to the existence of an attractive ‘heart’ deep inside the repulsive core.
openaire   +1 more source

A new window on Strange Quark Matter as the ground state of strongly interacting matter

open access: yes, 2003
If strange quark matter is the true ground state of matter, it must have lower energy than nuclear matter. Simultaneously, two-flavour quark matter must have higher energy than nuclear matter, for otherwise the latter would convert to the former. We show,
A. Gocksch   +21 more
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Charged lepton flavor violating decays with a pair of light dark matter and muonium invisible decay

open access: yesJournal of High Energy Physics
In this paper, we initiate the study of lepton flavor violating (LFV) dark matter (DM) interactions, expanding our focus beyond the flavor-conserving DM interactions typically considered in conventional direct and indirect detections.
Sahabub Jahedi, Yi Liao, Xiao-Dong Ma
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

High performance hybrid silicon micropillar solar cell based on light trapping characteristics of Cu nanoparticles

open access: yesAIP Advances, 2018
High performance silicon combined structure (micropillar with Cu nanoparticles) solar cell has been synthesized from N-type silicon substrates based on the micropillar array. The combined structure solar cell exhibited higher short circuit current rather
Yulong Zhang   +5 more
doaj   +1 more source

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