Results 81 to 90 of about 1,052,179 (350)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

High performance hybrid silicon micropillar solar cell based on light trapping characteristics of Cu nanoparticles

open access: yesAIP Advances, 2018
High performance silicon combined structure (micropillar with Cu nanoparticles) solar cell has been synthesized from N-type silicon substrates based on the micropillar array. The combined structure solar cell exhibited higher short circuit current rather
Yulong Zhang   +5 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Extensions of the Variational Method with an Explicit Energy Functional for Nuclear Matter with Spin-Orbit Force

open access: yesParticles
Two extensions of the variational method with explicit energy functionals (EEFs) with respect to the spin-orbit force were performed. In this method, the energy per nucleon of nuclear matter is explicitly expressed as a functional of various two-body ...
Kento Kitanaka   +4 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Saturation of nuclear matter and short-range correlations

open access: yes, 2003
A fully self-consistent treatment of short-range correlations in nuclear matter is presented. Different implementations of the determination of the nucleon spectral functions for different interactions are shown to be consistent with each other.
A. Ramos   +24 more
core   +1 more source

The Flow Constraint Influence on the Properties of Nuclear Matter Critical Endpoint [PDF]

open access: yes, 2017
We propose a novel family of equations of state for symmetric nuclear matter based on the induced surface tension concept for the hard-core repulsion.
Bravina, L. V.   +4 more
core   +2 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Hypercollapsed Nuclear Matter [PDF]

open access: yesSymposium - International Astronomical Union, 1974
We evoke the possible existence of hypercollapsed tightly bound nuclear isomers, due to the existence of an attractive ‘heart’ deep inside the repulsive core.
openaire   +1 more source

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