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Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
The EC Directive 2013/59/Euratom states in article 56 that exposures of target volumes in nuclear medicine treatments shall be individually planned and their delivery appropriately verified. The Directive also mentions that medical physics experts should
M. Konijnenberg+6 more
semanticscholar +1 more source
Nuclear medicine in endocrine tumours [PDF]
C
Peremans, Kathelijne+1 more
core +2 more sources
Image Formats: Five Years after the AAPM Standard for Digital Image Interchange [PDF]
The publication of AAPM Report No. 10 was the first attempt to standardize image formats in the medical imaging community. Since then, three other groups have formed (CART -- the Scandinavian collaboration for Computer Assisted Radiation Therapy ...
Maguire, Gerald Q., Noz, Marilyn E.
core +2 more sources
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Our purpose was to explore the reasons that a resident chooses to enter the nuclear medicine subspecialty in the integrated nuclear medicine and radiology residency program in The Netherlands.
Ton Velleman+4 more
semanticscholar +1 more source
Nuclear medicine: investigation of renal function in small animal medicine [PDF]
Kidney function investigations in veterinary medicine are traditionally based on blood analysis (blood urea nitrogen (BUN) and serum creatinine concentration) and / or urinalysis (urine specific gravity, protein-to-creatinine ratio or fractional ...
De Sadeleer, Carlos+7 more
core
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source
Recent activities of Boko Haram, a local extremist group in Nigeria, raise concerns about a nuclear terrorist attack. Whereas nuclear medicine (NM) relies on the timely delivery of radioactive sources, a robust security structure that assures public ...
T. Akintunde Orunmuyi+2 more
doaj +1 more source
The world is amidst a COVID-19 pandemic. It started in December 2019, when a new type of coronavirus 2019nCoV/SARS-CoV-2, causing the COVID-19 disease, was extracted and identified from the patient’s lower respiratory tract samples in Wuhan, China [1 ...
G. Gnanasegaran+9 more
semanticscholar +1 more source