Results 111 to 120 of about 3,281,539 (306)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Surrogate Model for In-Medium Similarity Renormalization Group Method Using Dynamic Mode Decomposition

open access: yesParticles
I propose a data-driven surrogate model for the In-Medium Similarity Renormalization Group (IMSRG) method using Dynamic Mode Decomposition (DMD). First, the Magnus formulation of the IMSRG is leveraged to represent the unitary transformation of many-body
Sota Yoshida
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Nuclear physics

open access: yes, 2014
This textbook explains the experimental basics, effects and theory of nuclear physics. It supports learning and teaching with numerous worked examples, questions and problems with answers.
Kamal, Anwar
core   +1 more source

Automatic Optimization of a Parallel-Plate Avalanche Counter with Optical Readout

open access: yesParticles
An automatic optimization procedure is proposed for some operational parameters of a Parallel-Plate Avalanche Counter with Optical Readout, a detector designed for heavy-ion tracking and imaging.
María Pereira Martínez   +2 more
doaj   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

open access: yesFEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez   +4 more
wiley   +1 more source

Nuclear physics: principles and applications

open access: yes, 2001
This title provides the latest information on nuclear physics. Based on a course entitled Applications of Nuclear Physics. Written from an experimental point of view this text is broadly divided into two parts, firstly a general introduction to Nuclear ...
Lilley, J S
core  

Exploring for oil with nuclear physics

open access: yesEPJ Web of Conferences, 2017
Oil↓eld service companies help identify and assess reserves and future production for oil and gas reservoirs, by providing petrophysical information on rock formations.
Mauborgne Marie-Laure   +5 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

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