Results 91 to 100 of about 315,285 (314)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

White paper on nuclear astrophysics and low energy nuclear physics Part 1: Nuclear astrophysics [PDF]

, 2017
This white paper informs the nuclear astrophysics community and funding agencies about the scientific directions and priorities of the field and provides input from this community for the 2015 Nuclear Science Long Range Plan. It summarizes the outcome of
Couture, Aaron J., Strohmayer, Tod E., Reddy, Sanjay, Zingale, Michael, Brune, Carl R., Schatz, Hendrik, Arcones, Almudena, Bardayan, Dan W., Danielewicz, Pawełl, Nunes, Filomena M., Chieffi, A., Danielewicz, Pawel, Fröhlich, Carla, Chieffi, Alessandro, Wiescher, Michael, McLaughlin, Gail C., Arcones Segovia, Almudena, Bernstein, Lee A., Messer, O. E.Bronson, El-Eid, Mounib F., Wiescher, Michael C., Steiner, Andrew W., O'Shea, Brian W., Champagne, Art E., Reddy, Sanjay K., Escher, Jutta E., Fields, Brian D., Zegers, Remco G. T., Diehl, Roland D., Stairs, Ingrid H., Zegers, Remco G.T., El-Eid, Mounib, Mezzacappa, Anthony, Townsley, Dean M., Meyer, Bradley S., Rutledge, Robert E., Pritychenko, Boris V., Rehm, Ernst, Champagne, Arthur E., Rogachev, Grigoriy V., Prakash, Madappa B.Nanda, Blackmon, Jeffery C., Timmes, F. X., Bardayan, Daniel W., Hix, William Raphael, Smith, Michael S., Rogachev, Grigory, Herwig, Falk, Nunes, Filomena, Prakash, Madappa, Meyer, Bradley Stewart, Blackmon, Jeffrey C., Pritychenko, Boris, Diehl, Roland, O’Shea, Brian W., Iliadis, Christian, Zingale, Michael A., Brown, B. Alex, Messer, Bronson, Beers, Timothy C., Lynch, William G., Smith, Michael Scott, Timmes, Francis X., Brown, Edward F.   +63 more
core   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

La Rábida 2018 International Scientific Meeting on Nuclear Physics [PDF]

, 2019
This book features material presented at the La Rabida 2018 International Scientific Meeting on Nuclear Physics, which was based on a well-known series of triennial international summer schools on Nuclear Physics organized from 1982 to 2003 by the Basic ...
Valera, Jose, Moro, Antonio, Garcia-Ramos, Jose-Enrique, Perez-Bernal, Francisco, Andres, Maria   +4 more
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Growth points in nuclear physics [PDF]

, 1980
Growth Points in Nuclear Physics, Volume 2 covers the progress in the fields of nuclear structure and nuclear reactions. This book is composed of three chapters.
Hodgson, Peter Edward
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An updated nuclear-physics and multi-messenger astrophysics framework for binary neutron star mergers. [PDF]

Nat Commun, 2023
Pang PTH, Dietrich T, Coughlin MW, Bulla M, Tews I, Almualla M, Barna T, Kiendrebeogo RW, Kunert N, Mansingh G, Reed B, Sravan N, Toivonen A, Antier S, VandenBerg RO, Heinzel J, Nedora V, Salehi P, Sharma R, Somasundaram R, Van Den Broeck C.   +20 more
europepmc   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Accelerating Innovation: How Nuclear Physics Benefits Us All [PDF]

, 2011
From fighting cancer to assuring food is safe to protecting our borders, nuclear physics impacts the lives of people around the globe every day. In learning about the nucleus of the atom and the forces that govern it, scientists develop a depth of ...

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