Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Proteins Connecting the Nuclear Pore Complex with the Nuclear Interior [PDF]
, 1999 Caterina Strambio‐De‐Castillia +2 more
openalex +1 more source
O-linked glycoproteins of the nuclear pore complex interact with a cytosolic factor required for nuclear protein import. [PDF]
, 1992 Rachel Sterne‐Marr +2 more
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In vivo analysis of protein crowding within the nuclear pore complex in interphase and mitosis [PDF]
, 2017 Hideaki Konishi +3 more
openalex +1 more source
Deciphering Networks of Protein Interactions at the Nuclear Pore Complex [PDF]
, 2002 Nadia P.C. Allen +7 more
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Percolation transition determines protein size limit for passive transport through the nuclear pore complex [PDF]
, 2021 David Winogradoff +3 more
openalex +1 more source
A monoclonal antibody against the nuclear pore complex inhibits nucleocytoplasmic transport of protein and RNA in vivo. [PDF]
, 1988 Carol Featherstone +2 more
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LINC complex alterations are a key feature of sporadic and familial ALS/FTD
Acta Neuropathologica CommunicationsAmyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder that primarily affects motor neurons, leading to progressive muscle weakness and loss of voluntary muscle control. While the exact cause of ALS is not fully understood, emerging research
Riccardo Sirtori +5 more
doaj +1 more source
Acting Out of Character: Regulatory Roles of Nuclear Pore Complex Proteins [PDF]
, 2009 Nikos Xylourgidis, Maarten Fornerod
openalex +1 more source