Results 71 to 80 of about 1,806,326 (359)

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Study on control rod worth measurement technique under deep subcritical condition

He jishu
BackgroundIn a series of startup physics tests, measuring the control rod worth is a critical means to determine whether the actual worth of the control rods matches the design values. This test ensures that the reactivity of the reactor can be precisely
SI Shengyi, BEI Hua, CHEN Lunshou, QIAN Zhongyou, DU Chao, GAO Mingmin, YANG Gaosheng   +6 more
doaj   +1 more source

Resonance-like nuclear processes in solids: 3rd and 4th order processes [PDF]

arXiv, 2013
It is recognized that in the family of heavy charged particle and electron assisted double nuclear processes resonance-like behavior can appear. The transition rates of the heavy particle assisted 3rd-order and electron assisted 4th-order resonance like double nuclear processes are determined. The power of low energy nuclear reactions in $Ni-H$ systems
arxiv  

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Landscape, environment and community impacts of nuclear power [PDF]

, 2012
This paper is the third in a series of 8 that make up the evidence base for SDC report 'The role of nuclear power in a low carbon economy'.This document investigates the landscape impacts of all the processes involved in nuclear power from mining the ...
Sustainable Development Commission
core  

Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification

FEBS Open Bio, EarlyView.
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski, Irene Cortijo, Shruti Bhargava, Bernard Jover, Fabrice Raynaud, Juliana H Boukhaled, Anne‐Dominique Lajoix, Vera Jankowski, Joachim Jankowski, Magali Cordaillat‐Simmons, Àngel Argilés, Nathalie Gayrard, Flore Duranton, Jonas Laget   +13 more
wiley   +1 more source

Can nuclear energy contribute to the energy transition? [PDF]

In the course of the energy transition, energy generation from nuclear power - through nuclear fission and perhaps in the future through nuclear fusion - is often proposed as an alternative or supplement to renewable energy sources. There are already good reasons why electricity generation from nuclear energy is significantly more expensive than other ...
arxiv   +1 more source

Underground nuclear power plant siting [PDF]

, 1972
This study is part of a larger evaluation of the problems associated with siting nuclear power plants in the next few decades. This evaluation is being undertaken by the Environmental Quality Laboratory of the California Institute of Technology in ...
Beck, R. L., Kammer, W. A., Langley, N. P., Selzer, L. A., Watson, M. B.   +4 more
core  

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

FEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna, Richard Buchal, Martin Leníček, Amit Shachak, Jan Pláteník   +4 more
wiley   +1 more source