Results 121 to 130 of about 1,246,840 (403)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

Retrotransposon Expression Is Upregulated in Adulthood and Suppressed during Regeneration of the Limb in the Axolotl (Ambystoma mexicanum)

open access: yesAdvanced Biology, EarlyView.
The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez   +8 more
wiley   +1 more source

Adaptive undervoltage protection scheme for safety bus in nuclear power plants

open access: yesNuclear Engineering and Technology, 2022
In the event of a short-circuit accident on a 4.16 kV non-safety bus, the voltage is temporarily lowered as backflow occurs on the safety bus. In such cases, the undervoltage relay of the safety bus shall not pick up the undervoltage so as not to ...
Choong-koo Chang
doaj  

Market Impacts of a Nuclear Power Plant Closure

open access: yes, 2016
Falling revenues and rising costs have put US nuclear plants in financial trouble, and some threaten to close. To understand the potential private and social consequences, we examine the abrupt closure of the San Onofre Nuclear Generating Station (SONGS)
Lucas W. Davis, Catherine Hausman
semanticscholar   +1 more source

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

open access: yesAdvanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim   +3 more
wiley   +1 more source

137Cs and 90Sr in the water of the ChNPP cooling pond [PDF]

open access: yesЯдерна фізика та енергетика, 2014
Results of long-term observations on 137Cs and 90Sr concentration in water mass of the ChNPP Cooling Pond are presented. Drastic transformation of the intrinsic trend in changes with time of averaged radionuclides con-tent in water is clearly ...
V. V. Kanivets   +4 more
doaj  

Handbook of human-reliability analysis with emphasis on nuclear power plant applications. Final report

open access: yes, 1983
The primary purpose of the Handbook is to present methods, models, and estimated human error probabilities (HEPs) to enable qualified analysts to make quantitative or qualitative assessments of occurrences of human errors in nuclear power plants (NPPs ...
A. D. Swain, H. Guttmann
semanticscholar   +1 more source

Prospects for Nuclear Power [PDF]

open access: yes
The prospects for a revival of nuclear power were dim even before the partial reactor meltdowns at the Fukushima nuclear plant. Nuclear power has long been controversial because of concerns about nuclear accidents, proliferation risk, and the storage of ...
Lucas W. Davis
core  

Don’t Give up on Nuclear Energy [PDF]

open access: yes, 2019
The nuclear power plant failures at Three Mile Island and Chernobyl in the late 1970s and 1980s split Americans into two passionate camps. For some, nuclear plants posed serious threats to both environmental and national security, and, for others ...
Gertner, Daniel
core   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

open access: yesAdvanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi   +4 more
wiley   +1 more source

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