Results 51 to 60 of about 8,240,057 (298)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Quantitative Assessment of Gaseous Effluents during Routine Operation: A Comparative Study of Planned Nuclear Power Plants at Lubiatowo-Kopalino and Pątnów Sites in Poland

Science and Technology of Nuclear Installations
On September 2021, Polish government declared that six pressurized water reactors with combined capacity of 6–9 GWe will be built by 2040 to reduce Poland’s reliance on coal. Due to the adopted schedule, construction of the first nuclear power plant will
Edyta Agata Macieja, Juyoul Kim
doaj   +1 more source

Studies on the correlation between irradiation hardening and thermal conductivity of RPV steel irradiated with protons

Journal of Materials Research and Technology
Reactor pressure vessel (RPV) is a critical safety component in nuclear power plants, and irradiation embrittlement induced by hardening is its primary safety challenge.
Chaoliang Xu, Wenqing Jia, Qiwei Quan, Yuanfei Li, Jian Yin, Huanchun Wu, Xiao Jin, Xianglong Guo, Xiangbing Liu   +8 more
doaj   +1 more source

New generation first-of-the kind unit – VVER-1200 design features

Nuclear Energy and Technology, 2017
The paper is concerned with the commissioning of the new generation NPP-2006 power unit with the VVER-1200 reactor. A comparison is made between the characteristics of the new NvNPP II-1 and commercial VVER-1000 power units (B-320).
V.G. Asmolov, I.N. Gusev, V.R. Kazanskiy, V.P. Povarov, D.B. Statsura   +4 more
doaj   +1 more source

Protection Coordination Index Assessment Using Fuzzy Logic Controller

Energies, 2022
This paper proposes the assessment method of the protection coordination index (PCI) for overcurrent protection relay and upstream relay. The protection coordination index is an indicator of how properly the equipment is protected by protective relay ...
Choong-Koo Chang, Ahmed Mohamed Elmashtoly   +1 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Human resource planning for authorized inspection activity

Nuclear Engineering and Technology, 2019
When newcomer countries consider a nuclear power programme, it is recognized that the most important organizations are the Nuclear Energy Programme Implementing Organization (NEPIO), the regulator, and an operating organization.
Seung-hee Lee, Robert Murray Field
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Study on Elastic-plastic fracture mechanics assessment method of a pipe having multiple circumferential surface cracks for the Rules on Fitness-for-Service of JSME

Nihon Kikai Gakkai ronbunshu, 2019
This paper describes elastic-plastic fracture mechanics assessment methods of a pipe having multiple circumferential cracks. Ductile fracture strength of a multiple cracked pipe was evaluated using J-integral based on a reference stress method.
Hideo MACHIDA, Toshiki OKAMOTO, Shinji YOSHIDA   +2 more
doaj   +1 more source