Results 91 to 100 of about 8,399,803 (398)

Medicago LINC complexes function in nuclear morphology, nuclear movement, and root nodule symbiosis 1[OPEN] [PDF]

, 2018
Nuclear movement is involved in cellular and developmental processes across eukaryotic life, often driven by Linker of Nucleoskeleton and Cytoskeleton (LINC) complexes, which bridge the nuclear envelope (NE) via the interaction of Klarsicht/ ANC-1/Syne-1
Cerro Sánchez, Pablo del, Charpentier, Myriam, Meier, Iris, Newman-Griffis, Anna H.   +3 more
core   +1 more source

Proteomics Approach to Identify Dehydration Responsive Nuclear Proteins from Chickpea (Cicer arietinum L.)*S

Molecular & Cellular Proteomics, 2008
Dehydration or water-deficit is one of the most important environmental stress factors that greatly influences plant growth and development and limits crop productivity.
Aarti Pandey, S. Chakraborty, A. Datta, N. Chakraborty   +3 more
semanticscholar   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

Tuning between Nuclear Organization and Functionality in Health and Disease

Cells, 2023
The organization of eukaryotic genome in the nucleus, a double-membraned organelle separated from the cytoplasm, is highly complex and dynamic. The functional architecture of the nucleus is confined by the layers of internal and cytoplasmic elements ...
Naresh Kumar Manda, Upendarrao Golla, Kishore Sesham, Parth Desai, Shrushti Joshi, Satyam Patel, Sharada Nalla, Susmitha Kondam, Lakhwinder Singh, Deepak Dewansh, Hemalatha Manda, Namita Rokana   +11 more
doaj   +1 more source

Nuclear Resonance Vibrational Spectroscopy of Iron Sulfur Proteins

, 2012
Nuclear inelastic scattering in conjunction with density functional theory (DFT) calculations has been applied for the identification of vibrational modes of the high-spin ferric and the high-spin ferrous iron-sulfur center of a rubredoxin-type protein ...
A. I. Chumakov, A. X. Trautwein, A.J.H. Wachters, B. Miehlich, C. Lee, C. Schmidt, H. Paulsen, H. Winkler, M.J. Frisch, P. Wegner, P. Wegner, P.J. Hay, R. Rüffer, R.S. Czernuszewicz, T.G. Spiro, T.R. Cundari, U. Bergmann, V. Schünemann, V. Schünemann, W.J. Stevens   +19 more
core   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Chromosome positioning is largely unaffected in lymphoblastoid cell lines containing emerin or A-type lamin mutations [PDF]

, 2005
Gene-poor human chromosomes are reproducibly found at the nuclear periphery in proliferating cells. There are a number of inner nuclear envelope proteins that may have roles in chromosome location and anchorage, e.g. emerin and A-type lamins.
Bridger, JM, Levy, N, Meaburn, KJ, Toniolo, D   +3 more
core   +1 more source

Identification of a novel autoantibody reactive with 155 and 140 kDa nuclear proteins in patients with dermatomyositis: an association with malignancy.

Rheumatology, 2007
OBJECTIVE Myositis-specific autoantibodies (MSAs) are a useful tool in diagnosis, defining clinical subsets and predicting prognosis of dermatomyositis (DM) and polymyositis (PM).
Kenzo Kaji, M. Fujimoto, M. Hasegawa, M. Kondo, Y. Saito, K. Komura, T. Matsushita, Hidemitsu Orito, Y. Hamaguchi, K. Yanaba, M. Itoh, Y. Asano, M. Seishima, F. Ogawa, S. Sato, K. Takehara   +15 more
semanticscholar   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

FEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt, Manuela Gellert, Finja Zelms, Sander Bekeschus, Christopher Horst Lillig   +4 more
wiley   +1 more source

Nuclear Envelope, Nuclear Lamina, and Inherited Disease [PDF]

, 2005
The nuclear envelope is composed of the nuclear membranes, nuclear lamina, and nuclear pore complexes. In recent years, mutations in nuclear-envelope proteins have been shown to cause a surprisingly wide array of inherited diseases.
Courvalin, Jean-Claude, Worman, Howard,
core   +4 more sources