Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies
Molecular Oncology, EarlyView.Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren +16 more
wiley +1 more source
AN EVALUATION OF THE BARRNETT AND SELIGMAN PROCEDURE WHEN USED TO DETERMINE CHANGES IN THE RATIO OF NUCLEAR PROTEIN-BOUND DISULFIDE TO SULFHYDRYL GROUPS DURING MITOSIS [PDF]
, 1961 Beal B. Hyde
openalex +1 more source
Reversal of terminal differentiation and control of DNA replication [PDF]
, 1993 DNA replication in mammalian cells occurs in discrete nuclear foci. Here we show that terminally differentiated myotubes can be induced to reenter S phase and show the same pattern of replication foci as cycling cells.
Cardoso, M. Cristina +2 more
core +1 more source
Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source
Zur Wirkung von Zn2⊕ auf die nucleare RNA- und Proteinbiosynthese der Rattenleber / Effect of Zn2⊕ on Nuclear RNA- and Protein-Biosynthesis in Rat Liver [PDF]
, 1969 Ulrich Weser, S. Seeber, P. Warnecke
openalex +1 more source
Functional analysis of plant Mei2-like proteins : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University, Palmerston North, New Zealand [PDF]
, 2003 Molecular techniques were used to analyse the function of a novel class of RNA-bindmg proteins in plants, termed Mei2-like. The biochemical function of this class of proteins is unclear Although the conserved presence of three RNA recognition motifs ...
Leung, Susanna Chui-Shan
core
A morphological view on mitochondrial protein targeting [PDF]
, 1994 Mitochondrial protein targeting includes both intramitochondrial sorting of proteins encoded by the organellar genome and import and subsequent sorting of nuclear encoded precursor proteins. Only a few proteins are encoded by the mitochondrial genome and
Ades +55 more
core +1 more source
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
Molecular Oncology, EarlyView.In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi +3 more
wiley +1 more source
Nuclear magnetic resonance studies of proteins. I. Conformational variance among members of the chymotrypsinogen family. [PDF]
, 1967 Donald P. Hollis +2 more
openalex +1 more source
Molecular Oncology, EarlyView.In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen +13 more
wiley +1 more source