Results 221 to 230 of about 1,026,366 (312)

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

ADP-ribosylation of isolated nuclei from HeLa cells, rat liver, fetal rat liver, and Novikoff hepatoma. Effect of nicotinamide adenine dinucleotide analogs on template activity for DNA synthesis, incorporation into nuclear proteins, and a new 1''-3' osidic linkage.

, 1977
Robert J. Suhadolnik, Roland Baur, D M Lichtenwalner, Takayoshi Uematsu, Jerry H. Roberts, S Sudhakar, Mark E. Smulson   +6 more
openalex   +1 more source

High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer

FEBS Open Bio, EarlyView.
Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson, Lisa Lif, Husam Oda, Alexandra Lorenzzi de Melo, David Lindquist, Håkan Hedman   +5 more
wiley   +1 more source

Nanobody-targeted E3-ubiquitin ligase complex degrades nuclear proteins. [PDF]

Sci Rep, 2015
Shin YJ, Park SK, Jung YJ, Kim YN, Kim KS, Park OK, Kwon SH, Jeon SH, Trinh le A, Fraser SE, Kee Y, Hwang BJ.   +11 more
europepmc   +1 more source

Nuclear magnetic resonance titration curves of histidine ring protons. Ribonuclease S-peptide and S-proteins.

, 1976
H. Shindo, Jack S. Cohen
openalex   +1 more source

The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions

FEBS Open Bio, EarlyView.
Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh, Esther Lee, Soo‐A Kim   +2 more
wiley   +1 more source

NLS-tagging: an alternative strategy to tag nuclear proteins. [PDF]

Nucleic Acids Res, 2014
Giraud G, Stadhouders R, Conidi A, Dekkers DH, Huylebroeck D, Demmers JA, Soler E, Grosveld FG.   +7 more
europepmc   +1 more source

Properties of a nuclear polyadenylate-protein complex from mouse ascites cells.

, 1977
Thomas J. Quinlan, Alan J. Kinniburgh, Terence E. Martin   +2 more
openalex   +1 more source

Downregulation of sST2, a decoy receptor for interleukin‐33, enhances subcutaneous tumor growth in murine pancreatic cancer cells

FEBS Open Bio, EarlyView.
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto, Nobuko Koshikawa, Takao Morinaga, Mimi Tamamori‐Adachi, Atsushi Takatori, Keizo Takenaga   +5 more
wiley   +1 more source

Degradation of specific nuclear proteins occurs in the cytoplasm in Saccharomyces cerevisiae. [PDF]

Genetics, 2014
Chen L, Madura K.
europepmc   +1 more source