Results 261 to 270 of about 12,222,224 (337)

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali, Priyanka Menon, Halil I. Corbali, Ram Jagannathan, Allan I. Levey   +4 more
wiley   +1 more source

Region Specific miRNA–mRNA Networks in Gray and White Matter Lesions of Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a neurodegenerative demyelinating disease of the central nervous system. This study aimed to identify micro‐RNA (miRNA)–mRNA regulatory networks underlying region‐specific molecular mechanisms in white matter and gray matter lesions in progressive MS.
Adya Sapra, Nagendra K. Rai, Timothy D. Niepokny, Haley Courtney, Ajai Tripathi, Ranjan Dutta   +5 more
wiley   +1 more source

Determinants of the Nucleocytoplasmic Balance of the Cucumber Mosaic Virus and Peanut Stunt Virus 2b Proteins Regulate the Subcellular Localization and RNA Silencing Suppressor Activity. [PDF]

Plants (Basel)
Pinczés D, Sáray R, Fábián A, Almási A, Salánki K.   +4 more
europepmc   +1 more source

Nuclear proteome analysis suggests spatial and temporal compartmentalization of metabolic enzymes during Trypanosoma cruzi cell cycle. [PDF]

PLoS Negl Trop Dis
Menezes AP, Gachet-Castro C, McGill S, Burchmore R, Silber A, Elias MC, da Cunha JPC.   +6 more
europepmc   +1 more source

Molecular Packaging, Liquid-Crystalline Order, and Three-Dimensional Architecture of Dinoflagellate Chromosomes. [PDF]

J Microbiol Biotechnol
Chung JM, Suzaki T, Fukuda Y, Song C.
europepmc   +1 more source

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Extraction of nuclear proteins.

Methods in molecular biology, 2007
The integrity of a subcellular proteome such as the nucleus, is largely dependent on purification of the isolated compartment away from other cellular contaminants. The separation of high-purity nuclei from plants is a difficult task. However, successful purification has been achieved through a series of fractionation processes.
S. Komatsu
semanticscholar   +3 more sources

Nuclear export of proteins: The role of nuclear retention

Cell, 1993
Proteins that shuttle between nucleus and cytoplasm are implicated in transport and signal transduction processes. Using assays based on interspecies heterokaryons and microinjection of Xenopus oocytes, we examined what structural features determine nuclear export of shuttling proteins.
Schmidt-Zachmann, M. S., Dargemont, C., Kühn, L. C., Nigg, E. A.   +3 more
openaire   +3 more sources

Nuclear protein localization

Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1991
L'article est une revue generale concernant le transport, apres synthese cytoplasmique, des proteines nucleaires dans le noyau a travers la membrane nucleaire. Les techniques d'etude sont presentees (techniques in vivo sur cellules, in vitro sur noyaux artificiels ou noyaux naturels reconstitues, approche genetique).
Garcia-Bustos, J., Heitman, J., Hall, M. N.   +2 more
openaire   +4 more sources

Nuclear Protein Transpor

Critical Reviews in Biochemistry and Molecular Biology, 1989
The nucleus, like all organelles, is composed of a unique set of proteins. This article discusses the possible mechanisms for localization of only certain proteins to the nucleus, transport of proteins across the nuclear envelope, and retention of proteins in the nuclear interior.
P, Silver, H, Goodson
openaire   +2 more sources