Results 31 to 40 of about 712,904 (293)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The first unbound states of mirror 9Be and 9B nuclei

open access: yesEPJ Web of Conferences, 2017
The structures of the first excited states of mirror 9Be and 9B nuclei are studied by using the α + α + N three-body model and the complex scaling method.
Odsuren Myagmarjav   +4 more
doaj   +1 more source

C12+16O molecular resonances at deep sub-barrier energy

open access: yesPhysics Letters B, 2020
The existence of C12+16O molecular resonances at sub-barrier energy has been a significant problem in nuclear astrophysics because they strongly affect the C12+16O fusion reaction rate in type Ia supernovae and heavy stars.
Yasutaka Taniguchi, Masaaki Kimura
doaj   +1 more source

Reinvestigating the Gamow Factor of Reactions on Light Nuclei

open access: yesThe Astrophysical Journal, 2023
We present a modified Gamow factor by reinvestigating the conventional assumptions used in its derivation. The conventional Gamow factor, factorized from the total cross section, effectively describes the penetration probabilities (PPs) in low-energy ...
Eunseok Hwang   +4 more
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

C12+12C fusion S⁎-factor from a full-microscopic nuclear model

open access: yesPhysics Letters B, 2021
The C12+12C fusion reaction plays a vital role in the explosive phenomena of the universe. The resonances in the Gamow window rule its reaction rate and products.
Yasutaka Taniguchi, Masaaki Kimura
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

A nuclear-reaction-based method for probing the nonthermal ion energy spectrum in high energy density laboratory plasmas

open access: yesNuclear Fusion, 2023
The nuclear reactions in a plasma system with particle distributions deviated from the Maxwellian are proved to have some unique characteristics, in particular, in their reaction product energy spectra.
K. Li   +5 more
doaj   +1 more source

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