Results 71 to 80 of about 7,332,961 (369)

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Neutron transfer and nuclear breakup in208Pb(11Li,9Li) reaction

open access: yesEurasian Journal of Physics and Functional Materials, 2021
Neutron transfer and nuclear breakup processes in reaction with weakly bound nucleus 11Li at energies near the Coulomb barrier are investigated in the framework of the time-dependent Schrödinger equation.
A. K. Azhibekov   +2 more
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Chiral symmetry and strangeness at SIS energies

open access: yes, 2003
In this talk we review the consequences of the chiral SU(3) symmetry for strangeness propagation in nuclear matter. Objects of crucial importance are the meson-baryon scattering amplitudes obtained within the chiral coupled-channel effective field theory.
Aichelin   +45 more
core   +2 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

A nuclear-reaction-based method for probing the nonthermal ion energy spectrum in high energy density laboratory plasmas

open access: yesNuclear Fusion, 2023
The nuclear reactions in a plasma system with particle distributions deviated from the Maxwellian are proved to have some unique characteristics, in particular, in their reaction product energy spectra.
K. Li   +5 more
doaj   +1 more source

Experimental study of three-nucleon dynamics in proton-deuteron breakup reaction [PDF]

open access: yes, 2017
Proton–deuteron breakup reaction can serve as a tool to test stateof- the-art descriptions of nuclear interactions. At intermediate energies, below the threshold for pion production, comparison of the data with exact theoretical calculations is ...
Ciepał, I.   +17 more
core   +5 more sources

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

open access: yesJournal of Cell Biology, 1992
Programmed cell death (PCD) plays a key role in developmental biology and in maintenance of the steady state in continuously renewing tissues. Currently, its existence is inferred mainly from gel electrophoresis of a pooled DNA extract as PCD was shown ...
Yael Gavrieli   +2 more
semanticscholar   +1 more source

Nuclear reaction uncertainties, massive gravitino decays and the cosmological lithium problem [PDF]

open access: yes, 2010
We consider the effects of uncertainties in nuclear reaction rates on the cosmological constraints on the decays of unstable particles during or after Big-Bang nucleosynthesis (BBN).
R. Cyburt   +5 more
semanticscholar   +1 more source

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

open access: yesFEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson   +7 more
wiley   +1 more source

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