Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Effect of compound nuclear reaction mechanism in 12C(Li6,d) reaction at sub-Coulomb energy
The angular distribution of the 12C(Li6,d) reaction populating the 6.92 and 7.12 MeV states of 16O at sub-Coulomb energy (E=cm3 MeV) are analysed in the framework of the Distorted Wave Born Approximation (DWBA).
Ashok Mondal, S. Adhikari, C. Basu
doaj +1 more source
From deep earth to deep stars: A different nuclear reaction path to generate calcium in ancient stars. [PDF]
Yan H, Shi J, Hou S.
europepmc +1 more source
Nuclear reaction data for IBA applications to cultural heritage diagnostics [PDF]
G. Maino, E. Menapace
openalex +1 more source
Protein O‐glycosylation in the Bacteroidota phylum
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns +2 more
wiley +1 more source
Sorption Mechanism of Europium by Apatite Using Rutherford Backscattering Spectroscopy and Resonant Nuclear Reaction Analysis. [PDF]
Toshihiko Ohnuki +6 more
openalex +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
A low-dose gamma irradiation was used for the one-step synthesis of graphene oxide/platinum nanoparticle composites. Various spectroscopic and microscopic methods were employed to structurally and morphologically characterize the prepared composites, and
Dejan Kepić +11 more
doaj +1 more source
Interplay between RNA‐protein interactions and RNA structures in gene regulation
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
Measurement and theoretical analysis of cross sections nuclear reaction (n, p), (n, α), (n, 2n) on isotopes of dysprosium, erbium and ytterbium [PDF]
Cross section of the nuclear reactions (n, p), (n, α), (n, 2n) were measured on isotopes of dysprosium, erbium and ytterbium at the neutron energies 14.6 ± 0.2 MeV.
O. M. Gorbachenko +5 more
doaj

