Results 41 to 50 of about 701 (211)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
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Partial Equilibrium Model for Nuclear Reactions [PDF]
Progress of Theoretical Physics, 1961 A new model for nuclear reactions is proposed in order to investigate the intermediate resonances'' detected experimentally in the intermediate energy region. The basic assumption is that only several nucleons of the target nucleus are excited at the compound system.
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Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
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Progress and Prospect of Basic Research on Nuclear Physics in China Institute of Atomic Energy
Yuanzineng kexue jishuThe recent progress and prospect on the nuclear physics at the China Institute of Atomic Energy (CIAE) was summarized in this paper. Significant advancements have been made in nuclear reaction mechanisms, nuclear structure, nuclear astrophysics, nuclear ...
YANG Lei, LIN Chengjian, LI Congbo, LI Gexing, ZHANG Yingxun, LYU Chong, JIA Huiming, ZHENG Yun, LI Yunju, GAO Zaochun, ZHAO Baozhen, WEN Peiwei, WU Xiaoguang, WANG Youbao, ZHAO Kai, XI Xiaofeng, LIAN Gang, YAN Shengquan, NAN Wei, LIAN Zhanjiang, MA Nanru, ZHAO Qiang, YANG Feng, YAN Yuliang, ZENG Sheng, LI Tianxiao, LIAO Junhui, HE Chuangye, WANG Zhao, SHEN Yangping, LI Zhihong, GUO Bing, LIU Weiping, WANG Naiyan, ZHANG Huanqiao
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
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Nature Communications, 2023 Boron neutron capture therapy (BNCT) was clinically approved in 2020 and exhibits remarkable tumour rejection in preclinical and clinical studies. It is binary radiotherapy that may selectively deposit two deadly high-energy particles (4He and 7Li ...
Yaxin Shi +11 more
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Nuclear Reactions at Moderate Energies and Fermi Gas Model [PDF]
Progress of Theoretical Physics, 1955 The cross secion fer r:uclccr:-r:uclrcn ccllistens in tbe nuclear matter is calculated in an aralytical way on the basts cf the Fermi gas mcdel ar:d the inverse ocergy nuckcn smttcnrg cross sectton. The mean free path thus denved 1s found to l:e m
Hayakawa, Satio +2 more
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Removing uncertainties from X-ray Busrt Models [PDF]
EPJ Web of ConferencesTwo of the astrophysically important reactions for X-ray burst models are 24Mg(α, γ)28Si and 59Cu(p, γ)60Zn. However, since these models are sensitive to nuclear reaction rates, it is important to constrain them to reduce possible model uncertainties ...
Singh Nisha +2 more
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