Results 91 to 100 of about 3,110,250 (305)

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

Unnuclear physics: Conformal symmetry in nuclear reactions. [PDF]

open access: yesProc Natl Acad Sci U S A, 2021
Hammer HW, Son DT.
europepmc   +1 more source

NUCLEAR CHEMISTRY ANNUAL REPORT 1970 [PDF]

open access: yes, 1971
Papers are presented for the following topics: (1) Nuclear Structure and Nuclear Properties - (a) Nuclear Spectroscopy and Radioactivity; (b) Nuclear Reactions and Scattering; (c) Nuclear Theory; and (d) Fission.
Various Authors, Authors, Various
core   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Nuclear reactions at intermediate energies

open access: yesEPJ Web of Conferences, 2016
In the domain of Nuclear reactions at intermediate energies, the QCD coupling constant αs is large enough (~ 0.3 - 0.5) to render the perturbative calculational techniques inapplicable. In this regime the quarks are confined into colorless hadrons and it
Shyam Radhey
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Coulomb distortion effects and determination of structure functions in quasifree (e,e'p) reactions

open access: yes, 1988
The role of Coulomb distortion of the electron waves on the determination of nuclear structure functions in quasifree (e,e'p) reactions is ...
PACATI, FRANCODAVIDE, GIUSTI, CARLOTTA
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Transfer reactions for nuclear astrophysics

open access: yesEPJ Web of Conferences, 2018
Direct measurements of cross sections at stellar energies are very challenging - if at all possible. This is essentially due to the very low cross-sections of the reactions of interest (especially when it involves charged particles), and/or to the ...
Hammache Fairouz
doaj   +1 more source

A study of light neutron-rich nuclei by two-body nuclear reactions

open access: yes, 1981
/sup 14/C or /sup 18/O-induced two-body nuclear reactions are used to measure the mass excess and in some cases the excited state energies of /sup 14/B, /sup 18/C, /sup 18/N and /sup 19/N.
Langevin, M   +8 more
core   +1 more source

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