FEBS Open Bio, EarlyView.CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama +7 more
wiley +1 more source
Analysis of Thick-Target Recoil Studies of High-Energy Nuclear Reactions [PDF]
, 1969 N. Porile
openalex +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Ultrashort Laser-Induced Nuclear Reactions: Initiating Decay of Helium Nuclei and Subsequent Fusion Reactions. [PDF]
ACS OmegaKovachev L +3 more
europepmc +1 more source
The Study of Chemical Reactions of Polyisoprenes by High Resolution Nuclear Magnetic Resonance
, 1965 Kei Matsuzaki, Kimiya FUJINAMI
openalex +2 more sources
Recoil Techniques in Nuclear Reaction and Fission Studies [PDF]
, 1960 B.G. Harvey
openalex +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Exploring artificial intelligence techniques to research low energy nuclear reactions. [PDF]
Front Artif IntellBari A, Garg TP, Wu Y, Singh S, Nagel D.
europepmc +1 more source
An Improved Particle Identifier for Studies of Low-Yield Nuclear Reactions [PDF]
, 1966 F.S. Goulding +3 more
openalex +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, EarlyView.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source