Results 1 to 10 of about 38 (37)

Long-term outcome of a 26-year-old woman with West syndrome and an nuclear receptor subfamily 2 group F member 1 gene (NR2F1) mutation [PDF]

Seizure, 2017
Long-term outcome of West syndrome with a NR2F1 mutation.
Naomi, Hino-Fukuyo, Atsuo, Kikuchi, Hiroyuki, Yokoyama, Kazuie, Iinuma, Mieko, Hirose, Kazuhiro, Haginoya, Tetsuya, Niihori, Keiko, Nakayama, Yoko, Aoki, Shigeo, Kure   +9 more
openaire   +4 more sources

LncRNA nuclear receptor subfamily 2 group F member 1 antisense RNA 1 (NR2F1-AS1) aggravates nucleus pulposus cell apoptosis and extracellular matrix degradation [PDF]

Bioengineered, 2022
Emerging reports uncover that long noncoding RNAs (lncRNAs) help regulate intervertebral disc degeneration (IVDD). Here, we probe the function of lncRNA nuclear receptor subfamily 2 group F member 1 antisense RNA 1 (NR2F1-AS1) in IVDD. Quantitative reverse transcription-polymerase chain reaction (qRT-PCR) was applied to verify the expression of NR2F1 ...
Du, Longlong, Li, Xuefeng, Gao, Qimeng, Yuan, Puwei, Sun, Yindi, Chen, Yingpu, Huang, Bo, Deng, Yu, Wang, Baohui   +8 more
openaire   +2 more sources

Novel NR2F1 variant identified by whole-exome sequencing in a patient with Bosch–Boonstra–Schaaf optic atrophy syndrome

Indian Journal of Ophthalmology, 2022
Bosch–Boonstra–Schaaf optic atrophy syndrome (BBSOAS) is an extremely rare autosomal dominant disorder characterized by intellectual disability, developmental delay, seizures, hypotonia, hearing loss, and optic nerve atrophy.
Ayca Kocaaga, Sevgi Yimenicioglu, Haluk Hüseyin Gürsoy   +2 more
doaj   +1 more source

METTL3 inhibits inflammation of retinal pigment epithelium cells by regulating NR2F1 in an m6A-dependent manner

Frontiers in Immunology, 2022
N6-metyladenosine (m6A) RNA methylation has been proven to be involved in diverse biological processes, but its potential roles in the development of lipopolysaccharide (LPS) induced retinal pigment epithelium (RPE) inflammation have not been revealed ...
Jiayu Meng, Jiayu Meng, Jiayu Meng, Xianyang Liu, Xianyang Liu, Xianyang Liu, Shiyun Tang, Shiyun Tang, Shiyun Tang, Yusen Liu, Yusen Liu, Yusen Liu, Chenyang Zhao, Chenyang Zhao, Chenyang Zhao, Qian Zhou, Qian Zhou, Qian Zhou, Na Li, Shengping Hou, Shengping Hou, Shengping Hou   +21 more
doaj   +1 more source

Low‐dose exercise protects the heart against established myocardial infarction via IGF‐1‐upregulated CTRP9 in male mice

MedComm, 2023
Regular exercise is recommended as an important component of therapy for cardiovascular diseases in clinical practice. However, there are still major challenges in prescribing an optimized exercise regimen to individual patients with established cardiac ...
Yanzhen Tan, Pan Feng, Lele Feng, Lei Shi, Yujie Song, Jian Yang, Weixun Duan, Erhe Gao, Jincheng Liu, Dinghua Yi, Bing Zhang, Yang Sun, Wei Yi   +12 more
doaj   +1 more source

Hypoxia-induced long noncoding RNA NR2F1-AS1 maintains pancreatic cancer proliferation, migration, and invasion by activating the NR2F1/AKT/mTOR axis

Cell Death and Disease, 2022
Accumulating evidence has demonstrated the essential role of long noncoding RNAs (lncRNAs) in various types of human cancer, including pancreatic cancer (PC). However, the functions and regulatory mechanisms of nuclear receptor subfamily 2 group F member
Yanqing Liu, Shiyu Chen, Kun Cai, Dijie Zheng, Changhao Zhu, Lin Li, Feiqing Wang, Zhiwei He, Chao Yu, Chengyi Sun   +9 more
doaj   +1 more source

A coregulatory network of NR2F1 and microRNA-140. [PDF]

PLoS ONE, 2013
Both nuclear receptor subfamily 2 group F member 1 (NR2F1) and microRNAs (miRNAs) have been shown to play critical roles in the developing and functional inner ear.
David Y Chiang, David W Cuthbertson, Fernanda R Ruiz, Na Li, Fred A Pereira   +4 more
doaj   +1 more source

DNA methylation of the glucocorticoid receptor gene predicts substance use in adolescence: longitudinal data from over 1000 young individuals

Translational Psychiatry, 2021
Early life stress has been linked to increased methylation of the Nuclear Receptor Subfamily 3 Group C Member 1 (NR3C1) gene, which codes for the glucocorticoid receptor.
Elena Raffetti, Philippe Anastasios Melas, Anton Jonatan Landgren, Filip Andersson, Yvonne Forsell, Catharina Lavebratt, Maria Rosaria Galanti   +6 more
doaj   +1 more source

The Nuclear Orphan Receptor NR2F6 Promotes Hepatic Steatosis through Upregulation of Fatty Acid Transporter CD36

Advanced Science, 2020
Nuclear receptors (NRs) are a superfamily of transcription factors which sense hormonal signals or nutrients to regulate various biological events, including development, reproduction, and metabolism.
Bing Zhou, Lijing Jia, Zhijian Zhang, Liping Xiang, Youwen Yuan, Peilin Zheng, Bin Liu, Xingxing Ren, Hua Bian, Liwei Xie, Yao Li, Jieli Lu, Huijie Zhang, Yan Lu   +13 more
doaj   +1 more source

The Nuclear Orphan Receptor NR2F6 Is a Central Checkpoint for Cancer Immune Surveillance

Cell Reports, 2015
Nuclear receptor subfamily 2, group F, member 6 (NR2F6) is an orphan member of the nuclear receptor superfamily. Here, we show that genetic ablation of Nr2f6 significantly improves survival in the murine transgenic TRAMP prostate cancer model ...
Natascha Hermann-Kleiter, Victoria Klepsch, Stephanie Wallner, Kerstin Siegmund, Sebastian Klepsch, Selma Tuzlak, Andreas Villunger, Sandra Kaminski, Christa Pfeifhofer-Obermair, Thomas Gruber, Dominik Wolf, Gottfried Baier   +11 more
doaj   +1 more source