Results 191 to 200 of about 6,710,080 (339)

Transcriptional control of apoptotic cell clearance by macrophage nuclear receptors

Apoptosis, 2016
Tamás Röszer
semanticscholar   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Integrated approaches to target nuclear receptors for managing the co-morbidity of tuberculosis and diabetes. [PDF]

Front Immunol
Arora R, Ahuja N, Kumawat S, Kaushal V, Sharma R, Gupta P.   +5 more
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Editorial: Nuclear receptors in health and disease. [PDF]

Front Endocrinol (Lausanne)
Santucci NE, Solt L, Carvalho VF.
europepmc   +1 more source

T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma.

Immunity, 2008
Xue-Xian O. Yang, B. Pappu, R. Nurieva, A. Akimzhanov, H. Kang, Yeonseok Chung, Li Ma, Bhavin Shah, Athanasia D. Panopoulos, K. Schluns, S. Watowich, Qiang Tian, A. Jetten, C. Dong   +13 more
semanticscholar   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Ligand Drift Rate Descriptor in Receptor Pocket: Molecular Docking Sampling for Differentiating Partial Agonists in Nuclear Receptors. [PDF]

J Chem Inf Model
Lin YT, Shih YT.
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Nuclear Regulatory Commission Report NUREG-0491

, 1978
From introduction: This Safety Evaluation Report summarizes the results of the technical evaluation of the proposed RESAR-414 design performed by the NRC staff, and delineates the scope of the technical matters considered in evaluating the radiological ...
U.S. Nuclear Regulatory Commission. Office of Nuclear Reactor Regulation.
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