Results 111 to 120 of about 1,272,933 (303)
U.S.-China strategic dialogue, phase II: conference report [PDF]
, 2007 The U.S.-China Strategic Dialogue brought together Chinese and U.S. strategic experts in their personal capacities to discuss to the role of nuclear weapons in Sino-American relations with the aim of minimizing mutual misunderstanding and identifying ...
Shelor, Kali, Twomey, Christopher P.
core +2 more sources
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Intrinsic factors responsible for brittle versus ductile nature of refractory high-entropy alloys
Nature CommunicationsRefractory high-entropy alloys (RHEAs) are of interest for ultrahigh-temperature applications. To overcome their drawbacks — low-temperature brittleness and poor creep strength at high temperatures — improved fundamental understanding is needed.
Tomohito Tsuru +9 more
doaj +1 more source
The Influence of Reaction Rates on the Final p-Abundances
, 2004 The astrophysical p-process is responsible for the origin of the proton rich nuclei,which are heavier than iron. A huge network involving thousands of reaction rates is necessary to calculate the final p-abundances.
Arnould +8 more
core +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Biological Threat Deterrence by Denial: Implications for Japan’s Nuclear Disarmament Vision
Journal for Peace and Nuclear DisarmamentJapan, a proponent of nuclear disarmament, is facing criticism for adopting “nuclear deterrence” as its foreseeable security policy without providing a clear strategy for transitioning away from it.
Kazuko Hikawa
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Japan as a Clean Energy Leader
, 2012 Over the past several decades, Japan’s energy strategy had positioned it as the world’s leader in clean and efficient electricity production and usage.
Norbom, Stefan N.
core +1 more source