Results 101 to 110 of about 545,425 (311)
POKER-X: An AI-enhanced and GPU-accelerated platform for rapid radiation shielding analysis
Nuclear Engineering and TechnologyThe increasing demand for rapid radiation-shielding assessment in nuclear engineering motivated the development of the POKER point-kernel code. To improve computational efficiency in large-scale and CAD-based shielding scenarios, the code has been re ...
Junyi Chen +5 more
doaj +1 more source
Effects of porous superhydrophilic surfaces on flow boiling critical heat flux in IVR accident scenarios [PDF]
, 2015 Critical Heat Flux (CHF) plays a key role in nuclear reactor safety both during normal operation as well as in accident scenarios. In particular,when an in-vessel retention (IVR) strategy is used as a severe accident management strategy, the reactor ...
Atkhen, Kresna +3 more
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
The Nuclear Imperative in Russia’s Security Strategy [PDF]
Revista CIDOB d'Afers Internacionals, 2005 The process which culminated in the disappearance of the USSR was heavily influenced by that Soviet Union’s inability to maintain the level of technology reached by the US in the arms race.
J. Oscar Alvarez Calzada
doaj
The Logic of American Nuclear Strategy
, 2018 What kind of nuclear strategy and posture does the United States need to defend itself and its allies? According to conventional wisdom, the answer to this question is straightforward: the United States needs the ability to absorb an enemy nuclear attack
Matthew Kroenig
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Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
The Trump Administration’s Nuclear Posture Review: Back to Great Power Competition
Journal for Peace and Nuclear Disarmament, 2018 The Nuclear Posture Review (NPR) covers all aspects of nuclear weapons policy – the role of nuclear weapons, the conditions under which the United States would consider the use of these weapons, the operational aspects of nuclear planning, force ...
Anna Péczeli
doaj +1 more source
, 2012 Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32166This article reviews the principles and methods of nuclear magnetic resonance spectroscopy, and gives examples of applications carried out at our Facility, which illustrate the ...
Molins i Montserrat, Mª Antònia +4 more
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