Results 81 to 90 of about 1,272,933 (303)

A comparative assessment of different deviation strategies for dangerous NEO [PDF]

, 2006
In this paper a number of deviation strategies for dangerous Near Earth Objects (NEO) have been compared. For each strategy (i.e. Solar Collector, Nuclear Blast, Kinetic Impactor, Low-thrust Propulsion, Mass Driver) a multi criteria optimisation method ...
Colombo, Camilla, Radice, Gianmarco, S. Cuartielles, Joan-Pau, Vasile, Massimiliano   +3 more
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Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

France’s Nuclear Defence Strategy towards the Prospects for European Nuclear Deterrence

Politeja
The crisis of multilateralism and the growing strategic and military rivalry between superpowers is changing the stability and balance of forces in the world.
Tomasz Młynarski
doaj   +3 more sources

Nuclear technology and the space exploration missions [PDF]

The strategy for a major exploration initiative leading to permanent human presence beyond earth orbit is still being developed; however enough is known to begin defining the role of nuclear technologies.
Brandhorst, Henry W., Sovie, Ronald J.
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Studies and Rejection of Intercrystal Crosstalk on FPGA in a High-Energy Photon-Counting System

Applied Sciences
Intercrystal scatter reduces system sensitivity and spatial resolution, a phenomenon that has been extensively studied in positron emission tomography (PET) systems. However, the issue is even more significant in high-energy systems.
Jiahao Chang, Huaxia Zhang, Shibo Jiang, Zhifang Wu, Shuo Xu   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Nuclear thermal propulsion test facility requirements and development strategy [PDF]

The Nuclear Thermal Propulsion (NTP) subpanel of the Space Nuclear Propulsion Test Facilities Panel evaluated facility requirements and strategies for nuclear thermal propulsion systems development.
Allen, George C., Clark, J. S., Warren, John   +2 more
core   +1 more source

Atlanta Consultation II: On the Future of the NPT [PDF]

, 2005
The Middle Powers Initiative, a program of the Global Security Institute, organized an Extraordinary Strategy Consultation on the Nuclear Non-proliferation Treaty (NPT) 2005 Review Conference in cooperation with former U.S.

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