Results 141 to 150 of about 959,641 (315)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Nuclear structure with coherent states

open access: yes, 2015
This book covers the essential features of a large variety of nuclear structure properties, both collective and microscopic in nature. Most of results are given in an analytical form thus giving deep insight into the relevant phenomena.
Raduta, Apolodor Aristotel
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Nuclear structure research in Australia: a briefing from Dr Eric Magnusson

open access: yes, 1984
A brief report on research on the structure of matter at basic level; emphasises work at the ANU and nuclear ...
Presenter: Eric Alfred Magnusson (1933-2009)   +1 more
core  

Projective vs. interpretational properties of nuclear accents and the phonology of contrastive focus in Greek

open access: yes, 2010
Georgakopoulos T, Skopeteas S. Projective vs. interpretational properties of nuclear accents and the phonology of contrastive focus in Greek. Linguistic Review. 2010;27(3):319-346.Nuclear accents have two interesting properties.
Georgakopoulos, Thanasis   +4 more
core   +2 more sources

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Learning from knockout reactions using a dispersive optical model

open access: yesFrontiers in Physics
We present the empirical dispersive optical model (DOM) as applied to direct nuclear reactions. The DOM links both scattering and bound-state experimental data through a dispersion relation, which allows for fully consistent, data-informed predictions ...
M. C. Atkinson, W. H. Dickhoff
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

A model study of nuclear structure functions

open access: yes, 1994
We calculate the structure function for a deuteron using the hadronic quark cluster decomposition. By assuming that nuclei might be composed of quasi deuterons, we study their structure functions.
Zambarda, A   +7 more
core   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

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