Results 31 to 40 of about 959,641 (315)

Lamin microaggregates lead to altered mechanotransmission in progerin-expressing cells

open access: yesNucleus, 2020
The nuclear lamina is a meshwork of intermediate filament proteins, and lamin A is the primary mechanical protein. An altered splicing of lamin A, known as progerin, causes the disease Hutchinson-Gilford progeria syndrome.
Brooke E. Danielsson   +7 more
doaj   +1 more source

Trends in the Structure of Nuclei near 100Sn

open access: yesPhysics, 2022
Inevitable progress has been achieved in recent years regarding the available data on the structure of 100Sn and neighboring nuclei. Updated nuclear structure data in the region is presented using selected examples.
Magdalena Górska
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Cellular and nuclear morphology…and calcium signaling: revealing the interplay between structure and function

open access: yes, 2012
Poster presentation: Calcium plays a pivotal role in relaying electrical signals of the cell to subcellular compartments, such as the nucleus. Since this one ion type is used by the cell for many processes a neuron needs to establish finely tuned calcium
Queisser, Sean Gillian   +4 more
core   +1 more source

Towards p-11B medium configurations with high Pfus/PBrems ratios

open access: yesFrontiers in Physics
Aneutronic p-11B nuclear fusion is promising for clean energy production, as it produces three (3) alpha particles with 8.7 MeV total energy. However, the main difficulty for p-11B fusion ignition (Q = Pfus/PBrems≥ 1) concerns the nuclear cross section ...
C. Daponta   +6 more
doaj   +1 more source

Nuclear structure of 231Ac [PDF]

open access: yesNuclear Physics A, 2008
Abstract The low-energy structure of 231Ac has been investigated by means of γ ray spectroscopy following the β − decay of 231Ra. Multipolarities of 28 transitions have been established by measuring conversion electrons with a mini-orange electron spectrometer. The decay scheme of 231Ra → 231Ac has been constructed for the first time.
R. Boutami   +12 more
openaire   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Discovery and restoration of Aberrant Nuclear structure and Genome behaviour in breast cancer cells [PDF]

open access: yes, 2013
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The eukaryotic interphase nucleus is well organised and the genome positioned non-randomly.
Hassan Ahmed, Mai
core  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Energy- and temperature-dependent transport of integral proteins to the inner nuclear membrane via the nuclear pore [PDF]

open access: yes, 2004
Resident integral proteins of the inner nuclear membrane (INM) are synthesized as membrane-integrated proteins on the peripheral endoplasmic reticulum (ER) and are transported to the INM throughout interphase using an unknown trafficking mechanism.
Gerace, Larry   +7 more
core   +1 more source

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