Results 51 to 60 of about 959,641 (315)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Isobaric analog resonances of Mg31 and the border of the island of inversion

open access: yes, 2014
The evolution of the nuclear shell structure in the region of the neutron-rich shell-breaking nucleus Mg32 has been the subject of considerable interest. We present here the first determination of the overlap of the ground and two first excited states in
Imai, N   +25 more
core   +1 more source

Centrifugal stretching of 170Hf in the interacting boson model

open access: yesEPJ Web of Conferences, 2014
We present the results of a recent experiment to deduce lifetimes of members of the ground state rotational band of 170Hf, which show the effect of centrifugal stretching in this deformed isotope.
Werner V., Pietralla N., Smith M. K.
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Diagnostic CT organ dose estimation in whole-body PET/CT examinations–comparison of a patient-specific monte carlo approach and a computational phantom-based CT dosimetry tool

open access: yesEJNMMI Physics
Background Studies evaluating the impact of advances in CT dosimetry tools on CT organ dose estimations are often limited to a comparison with TLD measurements in anthropomorphic phantoms or a comparison of different dosimetry tools using computational ...
Gwenny Verfaillie   +2 more
doaj   +1 more source

STUDYING THE NUCLEAR STRUCTURE OF EVEN-EVEN DEFORMED GERMANIUM NUCLEUS [PDF]

open access: yesمجلة جامعة الانبار للعلوم الصرفة, 2012
In the present work, the interacting boson model(IBM-1) for s and d boson is used to calculate the energy levels of the positive parity bands, electric quadrupole moments, E2-transition probabilities B(E2)in particular between states which may be ...
ALI KALAF AOBAID
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Nuclear structure information obtained from charge radii

open access: yes, 1985
We analyze the nuclear structure information obtained from measurements of charge radii in even-even and even-odd nuclei terms of the interacting boson model.
Iachello, F.   +2 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Polypeptide components of Drosophila small nuclear ribonucleoprotein particles [PDF]

open access: yes, 1991
In eukaryotes splicing of pre-mRNAs is mediated by the spliceosome, a dynamic complex of small nuclear ribonucleoprotein particles (snRNPs) that associate transiently during spliceosome assembly and the splicing reaction.
FINNEGAN, D J   +4 more
core   +1 more source

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