Results 71 to 80 of about 959,641 (315)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Effects of Nuclear Structure in Heavy Element Formation Dynamics

, 2016
The effects of nuclear structure can be manifested at three stages of the reaction dynamics: through the effect of channel couplings in overcoming the entrance channel potential barrier; in damping of the relative motion leading to capture; and in ...
du Rietz, Rickard, Evers, Maurits, Simenel, Cedric, Wakhle, Aditya, Dasgupta, Mahananda, Luong, Huy, Hinde, David   +6 more
core   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

SUMOylation of nuclear actin [PDF]

, 2009
Actin, a major component of the cytoplasm, is also abundant in the nucleus. Nuclear actin is involved in a variety of nuclear processes including transcription, chromatin remodeling, and intranuclear transport.
Alessandro Arduini, Lessard, James L., Arduini, Alessandro, Nicol, Samantha M., Fuller-Pace, Frances V., Primal de Lanerolle, Samantha M. Nicol, Frances V. Fuller-Pace, Carlos J. Camacho, James L. Lessard, de Lanerolle, Primal, Wilma A. Hofmann, Camacho, Carlos J., Hofmann, Wilma A.   +13 more
core   +1 more source

Selective Ablation and Laser-Induced Periodical Surface Structures (LIPSS) Produced on (Ni/Ti) Nano Layer Thin Film with Ultra-Short Laser Pulses

Photonics
The interaction of ultra-short laser pulses (USLP) with Nickel/Titanium (Ni/Ti) thin film has been presented. The nano layer thin film (NLTF), composed of ten alternating Ni and Ti layers, was deposited on silicon (Si) substrate by ion-sputtering.
Biljana Gaković, Suzana Petrović, Christina Siogka, Dubravka Milovanović, Miloš Momčilović, George D. Tsibidis, Emmanuel Stratakis   +6 more
doaj   +1 more source

Ground State Properties of Even-Even 30−92Ca Isotopes Using HFB Theory. [PDF]

Kirkuk Journal of Science
Ground State (GS) Properties of Even-Even isotopes have been studied in frame of Skyrme Hartree-Fock-Bogoliubov using computer program HFBTHO V3.00 with three types of Skyrme interactions (HFB9, SLY4 and SLY5). The calculated nuclear properties including
Pshkow Mahmood
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source