Results 91 to 100 of about 8,482,913 (303)
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
We have constructed a large field N-flation model in the supergravity framework. In this simple set-up, N fields collectively drive inflation where each field traverses sub-Planckian field values.
Kumar Das, Koushik Dutta
doaj +1 more source
Appearance of branched motifs in the spectra of BCN type Polychronakos spin chains
As is well known, energy levels appearing in the highly degenerate spectra of the AN−1 type of Haldane-Shastry and Polychronakos spin chains can be classified through the motifs, which are characterized by some sequences of the binary digits like ‘0’ and
Bireswar Basu-Mallick, Madhurima Sinha
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Nuclear forces: Theory and applications [PDF]
I review the status of nuclear chiral effective field theory and discuss selected applications focusing on current topics such as the structure of three-nucleon force. I also discuss the discretized version of this approach which treats pions and nucleons as point-like particles on an Euclidean space-time lattice.
openaire +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Complexity in Economic and Social Systems: Cryptocurrency Market at around COVID-19
Social systems are characterized by an enormous network of connections and factors that can influence the structure and dynamics of these systems. Among them the whole economical sphere of human activity seems to be the most interrelated and complex. All
Stanisław Drożdż +4 more
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source

