Results 61 to 70 of about 1,147,829 (292)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
A new approach to barrier-top fission dynamics
EPJ Web of Conferences, 2016 We proposed a calculational framework for describing induced fission that avoids the Bohr-Wheeler assumption of well-defined fission channels. The building blocks of our approach are configurations that form a discrete, orthogonal basis and can be ...
Bertsch G.F., Mehlhaff J.M.
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Neutron Stars and the Cosmological Constant Problem
, 2011 The gravitational aether theory is a modification of general relativity that decouples vacuum energy from gravity, and thus can potentially address the cosmological constant problem. The classical theory is distinguishable from general relativity only in
C. M. Will +4 more
core +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Wormholes and holography: an introduction
European Physical Journal C: Particles and Fields, 2022 Wormholes are intriguing classical solutions in General Relativity, that have fascinated theoretical physicists for decades. In recent years, especially in Holography, gravitational Wormhole geometries have found a new life in many theoretical ideas ...
Arnab Kundu
doaj +1 more source
The continuum discretized coupled-channels method and its applications
, 2012 This is a review on recent developments of the continuum discretized coupled-channels method (CDCC) and its applications to nuclear physics, cosmology and astrophysics, and nuclear engineering.
Matsumoto, Takuma +3 more
core +1 more source
Challenges in nuclear structure theory [PDF]
Journal of Physics G: Nuclear and Particle Physics, 2016 The goal of nuclear structure theory is to build a comprehensive microscopic framework in which properties of nuclei and extended nuclear matter, and nuclear reactions and decays can all be consistently described. Due to novel theoretical concepts, breakthroughs in the experimentation with rare isotopes, increased exchange of ideas across different ...
openaire +2 more sources
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source