Results 131 to 140 of about 418,889 (263)

Reprogramming barriers in bovine cells nuclear transfer revealed by single-cell RNA-seq analysis. [PDF]

J Cell Mol Med, 2022
Zhao L, Long C, Zhao G, Su J, Ren J, Sun W, Wang Z, Zhang J, Liu M, Hao C, Li H, Cao G, Bao S, Zuo Y, Li X.   +14 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Derivation of embryonic stem cells from cloned blastocysts using improved somatic cell nuclear transfer in common marmosets. [PDF]

Stem Cell Reports
Matoba S, Kurotaki Y, Funaya S, Yamada Y, Ogonuki N, Shinohara H, Yamamoto M, Yoneda N, Homma T, Higuchi Y, Sasaki E, Ogura A.   +11 more
europepmc   +1 more source

Interspecific Nuclear Transfer Blastocysts Reconstructed from Arabian Oryx Somatic Cells and Domestic Cow Ooplasm. [PDF]

Vet Sci, 2022
Ammari AA, ALGhadi MG, Amran RA, Al Malahi NM, Alhimaidi AR.   +4 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Efficient Somatic Cell Nuclear Transfer by Overcoming Both Pre- and Post-Implantation Epigenetic Barriers. [PDF]

Adv Sci (Weinh)
Li Y, Sun S, Xu Y, Zhang J, Du Y, Cao Y, Liao Z, Xie Y, Bian X, Huang J, Wang M, Liu Z, Sun Q, Lu F.   +13 more
europepmc   +1 more source

Strategies to Improve the Efficiency of Somatic Cell Nuclear Transfer. [PDF]

Int J Mol Sci, 2022
Srirattana K, Kaneda M, Parnpai R.
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Lycopene enhances epigenetic reprogramming and zygotic genome activation in the porcine somatic cell nuclear transfer embryo. [PDF]

Sci Rep
Yun JH, Kang HG, Choi EY, Jeon SB, Kim MJ, Jeong PS, Song BS, Kim SU, Min KS, Sim BW.   +9 more
europepmc   +1 more source

25th ANNIVERSARY OF CLONING BY SOMATIC-CELL NUCLEAR TRANSFER: Nuclear transfer and the development of genetically modified/gene edited livestock. [PDF]

Reproduction, 2021
Alberio R, Wolf E.
europepmc   +1 more source