Results 141 to 150 of about 418,889 (263)

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

H3K9me3 and H3K27me3 are epigenetic barriers to somatic cell nuclear transfer in rabbits. [PDF]

Am J Transl Res
Gao Y, Wu F, Tang D, Chen X, Chen Q, Chen Y, Fang K, Chen W, Du F, Liu Z.   +9 more
europepmc   +1 more source

Effect of Mechanical Micro-Vibrations on The Efficiency of Leopard Inter-Species Somatic Cell Nuclear Transfer. [PDF]

Cell J, 2022
Shahverdi M, Akbarinejad V, Dalman A, Hajinasrollah M, Vodjgani M, Tanhaei Vash N, Nasr-Esfahani MH, Eftekhari-Yazdi P.   +7 more
europepmc   +1 more source

Nuclear Transfer [PDF]

, 2020
openaire   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

The Complexities of Interspecies Somatic Cell Nuclear Transfer: From Biological and Molecular Insights to Future Perspectives. [PDF]

Int J Mol Sci
Pankammoon P, Salinas MBS, Thitaram C, Sathanawongs A.   +3 more
europepmc   +1 more source

Suppression of endogenous retroviral enhancers in mouse embryos derived from somatic cell nuclear transfer. [PDF]

Front Genet, 2022
Shikata D, Matoba S, Hada M, Sakashita A, Inoue K, Ogura A.   +5 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

The Role of Somatic Cell Synchronization in Nuclear Transfer and Induced Pluripotent Stem Cells for Wild Felids. [PDF]

Zoo Biol
Viana JVS, Pereira AF.
europepmc   +1 more source

Farrerol directly activates the deubiqutinase UCHL3 to promote DNA repair and reprogramming when mediated by somatic cell nuclear transfer. [PDF]

Nat Commun, 2023
Zhang W, Wang M, Song Z, Fu Q, Chen J, Zhang W, Gao S, Sun X, Yang G, Zhang Q, Yang J, Tang H, Wang H, Kou X, Wang H, Mao Z, Xu X, Gao S, Jiang Y.   +18 more
europepmc   +1 more source