Results 161 to 170 of about 4,128,907 (296)

Mechanical strain treatment improves nuclear transfer reprogramming efficiency by enhancing chromatin accessibility. [PDF]

open access: yesStem Cell Reports, 2023
Chen Y   +12 more
europepmc   +1 more source

Selecting dynamic nuclear polarization pathways in an electron-nuclear system

open access: yes, 2013
Thesis (Ph. D.)--Massachusetts Institute of Technology, Department of Nuclear Science and Engineering, 2013.Cataloged from PDF version of thesis.Includes bibliographical references (pages 101-107).There is much interest in improving quantum control ...
Sheldon, Sarah (Sarah Elizabeth)
core  

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Nuclear Systems Design Project

open access: yes, 2002
Group design project involving integration of nuclear physics, particle transport, control, heat transfer, safety, instrumentation, materials, environmental impact, and economic optimization.
Kadak, Andrew
core  

Threonine 348 regulates the subcellular localization of PTEN

open access: yesFEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

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