Results 11 to 20 of about 418,889 (263)

Mitochondrial DNA Depletion in Granulosa Cell Derived Nuclear Transfer Tissues

Frontiers in Cell and Developmental Biology, 2021
Somatic cell nuclear transfer (SCNT) is a key technology with broad applications that range from production of cloned farm animals to derivation of patient-matched stem cells or production of humanized animal organs for xenotransplantation.
Daniela Bebbere, Daniela Bebbere, Susanne E. Ulbrich, Katrin Giller, Valeri Zakhartchenko, Horst-Dieter Reichenbach, Horst-Dieter Reichenbach, Myriam Reichenbach, Myriam Reichenbach, Paul J. Verma, Paul J. Verma, Eckhard Wolf, Sergio Ledda, Stefan Hiendleder, Stefan Hiendleder, Stefan Hiendleder, Stefan Hiendleder   +16 more
doaj   +1 more source

Investigation of the Thermal Performance of a Vertical Two-Phase Closed Thermosyphon as a Passive Cooling System for a Nuclear Reactor Spent Fuel Storage Pool

Nuclear Engineering and Technology, 2017
The decay heat that is produced by nuclear reactor spent fuel must be cooled in a spent fuel storage pool. A wickless heat pipe or a vertical two-phase closed thermosyphon (TPCT) is used to remove this decay heat.
Mukhsinun Hadi Kusuma, Nandy Putra, Anhar Riza Antariksawan, Susyadi, Ficky Augusta Imawan   +4 more
doaj   +1 more source

Determination of Oocyte-Manipulation, Zygote-Manipulation, and Genome-Reprogramming Effects on the Transcriptomes of Bovine Blastocysts

Frontiers in Genetics, 2018
Somatic cell nuclear transfer (scNT) embryos suffer from damage caused by micro-operation (manipulation) and inefficient genome reprograming that hinder their normal development at different levels and in distinct ways.
Byungkuk Min, Jung S. Park, Yong-Kook Kang   +2 more
doaj   +1 more source

Nuclear transfer in rodents

The Journal of Physiology, 2003
Cloning is the asexual reproduction of an individual, such that the offspring have an essentially identical nuclear genome. Nuclear transfer and cloning have been achieved in a number of species, namely sheep, cows, goats, rabbits, cats and mice, but have been largely unsuccessful, so far, in dogs, primates and rats. Clearly, contributory factors which
Linda J, Mullins, Ian, Wilmut, John J, Mullins   +2 more
openaire   +3 more sources

The mRNA expression of brain-derived neurotrophic factor in oocytes and embryos and its effects on the development of early embryos in cattle

Animal, 2008
The aims of the study were to measure the mRNA expression of brain-derived neurotrophic factor (BDNF) in bovine oocytes and early embryos derived from in vitro fertilization (IVF), parthenogenetic activation (PA) and nuclear transfer (NT), and to ...
K.L. Yi, X. Zhou, D.S. Shi, H.H. Chen, Q.L. Qin, Y. Chen, C.J. Li, Z.H. Zhao, S.Y. Xing   +8 more
doaj   +1 more source

Somatic Cell Nuclear Transfer [PDF]

Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics, 2003
Embryos produced by nuclear transfer from a patient's somatic cell offer one potential source of embryonic stem cells for treatment of human degenerative diseases. As with all of the approaches to such therapy, this has both strengths and weaknesses.
Ian, Wilmut, Lesley, Paterson
openaire   +6 more sources

Efeito do número da passagem e do gênero das células doadoras de núcleo no desenvolvimento de bovinos produzidos por transferência nuclear Effect of culture time and gender of nuclei donor cells on bovine development produced by nuclear transfer

Revista Brasileira de Zootecnia, 2010
Objetivou-se com este trabalho avaliar o efeito do número da passagem e do sexo das células doadoras de núcleo no desenvolvimento embrionário e fetal após transferência nuclear.
Giovana Krempel Fonseca Merighe, Moysés dos Santos Miranda, Tiago Henrique Câmara de Bem, Yeda Fumie Watanabe, Flávio Vieira Meirelles   +4 more
doaj   +1 more source

Various nuclear reprogramming systems using egg and oocyte materials

The Journal of Reproduction and Development, 2019
Maternal factors stored in eggs and oocytes are necessary for reprogramming sperm for embryonic development. This reprogramming activity of maternal factors also works towards somatic cells, including terminally differentiated cells.
Kei MIYAMOTO
doaj   +1 more source

Aberrant imprinting in mouse trophoblast stem cells established from somatic cell nuclear transfer-derived embryos

Epigenetics, 2018
Although phenotypic abnormalities frequently appear in the placenta following somatic cell nuclear transfer (SCNT), mouse trophoblast stem cells (TSCs) established from SCNT embryos reportedly show no distinct abnormalities compared with those derived ...
Michiko Hirose, Masashi Hada, Satoshi Kamimura, Shogo Matoba, Arata Honda, Kaori Motomura, Narumi Ogonuki, Hossam H. Shawki, Kimiko Inoue, Satoru Takahashi, Atsuo Ogura   +10 more
doaj   +1 more source

Comparison of in vitro Neuronal Differentiation Capacity Between Mouse Epiblast Stem Cells Derived From Nuclear Transfer and Naturally Fertilized Embryos

Frontiers in Molecular Neuroscience, 2018
Somatic cell nuclear transfer (SCNT) can give rise to fertile adults, but the successful perinatal and postnatal developmental rates are inefficient, including delayed developmental behaviors, and respiratory failure.
Tong Li, Yi Zheng, Yan Li, Danna Ye
doaj   +1 more source